| 词条 | 4-Methylcathinone |
| 释义 |
| verifiedrevid = | IUPAC_name = 2-amino-1-(4-methylphenyl)propan-1-one | image = 4-Methylcathinone.png | width = 220 | image2 = 4-MethylCathinone.png | tradename = | legal_CA = Schedule I | legal_UK = Class B | legal_status = | CAS_number_Ref = | CAS_number = 31952-47-3 | CAS_number2 = 6941-17-9 | index_label = | index2_label = HCl | DrugBank_Ref = | PubChem = 414532 | ChemSpiderID = 367058 | UNII = CY9HK59OK6 | C=10 | H=13 | N=1 | O=1 | molecular_weight = 163.219 g/mol | smiles = CC1=CC=C(C=C1)C(=O)C(C)N | StdInChI = 1S/C10H13NO/c1-7-3-5-9(6-4-7)10(12)8(2)11/h3-6,8H,11H2,1-2H3 | StdInChIKey = OHULHWHSUJEYIT-UHFFFAOYSA-N }}4-Methylcathinone (also known as Nor-Mephedrone, 4-MC and NSC-60487), is a stimulant drug of the cathinone chemical class that has been sold online as a designer drug.[1] It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).[2][3][4] 4-Methylcathinone displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone.[5] See also
References1. ^{{cite web | url=https://www.caymanchem.com/app/template/Product.vm/catalog/9000940 | title=nor-Mephedrone | publisher=Cayman Chemical | accessdate=27 June 2015}} {{Stimulants}}{{Phenethylamines}}{{Entactogens}}{{DEFAULTSORT:Methylcathinone, 4-}}{{nervous-system-drug-stub}}2. ^{{cite journal | title=Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography–mass spectrometry | author=Markus R. Meyer | author2=Jens Wilhelm | author3=Frank T. Peters| author4=Hans H. Maurer | journal=Analytical and Bioanalytical Chemistry |date=June 2010 | volume=397 | issue=3 | pages=1225–1233 | doi=10.1007/s00216-010-3636-5 | pmid=20333362}} 3. ^{{cite journal | title=In vitro metabolism studies on mephedrone and analysis of forensic cases | date=June 2013 | author=Anders Just Pedersen | author2=Lotte Ask Reitzel | author3=Sys Stybe Johansen | author4=Kristian Linnet | journal=Drug Testing and Analysis | volume=5 | issue=6 | pages=430–438 | doi=10.1002/dta.1369 | pmid=22573603}} 4. ^{{cite journal | title=The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone) | date=July–August 2011 | author=Paul I. Dargan | author2=Roumen Sedefov | author3=Ana Gallegos | author4=Dr David M. Wood | journal=Drug Testing and Analysis | volume=3 | issue=7–8 | pages=454–463 | doi=10.1002/dta.312 | pmid=21755604}} 5. ^{{cite journal | url=http://www.sciencedirect.com/science/article/pii/S0924977X15003934 | title=Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats | date=February 2016 | author=Blake A. Hutsell | author2=Michael H. Baumann | author3=John S. Partilla | author4=Matthew L. Banks | author5=Rakesh Vekariya | author6=Richard A. Glennon | author7=S. Stevens Negus | journal=European Neuropsychopharmacology | volume=26 | issue=2 | pages=288–297 | doi=10.1016/j.euroneuro.2015.12.010 | pmid=26738428| pmc=5331761 }} 3 : Cathinones|Designer drugs|Serotonin-dopamine releasing agents |
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