词条 | 5F-ADBICA |
释义 |
| IUPAC_name = N-(1-Amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(5-fluoropentyl)-1H-indole-3-carboxamide | image = 5F-ADBICA_structure.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = Schedule II | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 1801338-27-1 | ATC_prefix = | ATC_suffix = | PubChem = | ChemSpiderID = 29342128 | C=20 | H=28 | N=3 | O=2 | F=1 | molecular_weight = 361.46 g/mol | smiles = FCCCCCn1cc(c2c1cccc2)C(=O)NC(C(C)(C)C)C(=O)N | StdInChI = 1S/C20H28FN3O2/c1-20(2,3)17(18(22)25)23-19(26)15-13-24(12-8-4-7-11-21)16-10-6-5-9-14(15)16/h5-6,9-10,13,17H,4,7-8,11-12H2,1-3H3,(H2,22,25)(H,23,26) | StdInChIKey = ITZSOCZDFSHNCL-UHFFFAOYSA-N }}5F-ADBICA (also known as 5F-ADB-PICA) is an indole-based synthetic cannabinoid that is a potent agonist at CB1 receptors and CB2 receptors with EC50 values of 0.77 nM and 1.2 nM respectively.[1][2] Legal StatusChinaAs of October 2015 5F-ADBICA is a controlled substance in China.[3] See also{{div col|colwidth=30em}}
References1. ^{{cite journal | title=The pharmacology of indole and indazole synthetic cannabinoid designer drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA and 5F-ADBICA | author=Samuel D Banister | author2=Michael Moir | author3=Jordyn Stuart| author4=Richard C Kevin | author5=Katie E Wood| author6=Mitchell Longworth | author7=Shane M Wilkinson| author8=Corinne Beinat | author9=Alxendra S Buchanan| author10=Michelle Glass | author11=Mark Connor| author12=Iain S McGregor | author13=Michael Kassiou | journal=ACS Chemical Neuroscience |date=July 2015 | doi=10.1021/acschemneuro.5b00112 | pmid=26134475 | volume=6 |issue = 9| pages=1546–59}} {{Cannabinoids}}{{cannabinoid-stub}}2. ^{{cite web | url=http://forendex.southernforensic.org/index.php/detail/index/1262 | title=5F-ADBICA | publisher=Southern Association of Forensic Scientists | accessdate=21 July 2015}} 3. ^{{cite web | url=http://www.sfda.gov.cn/WS01/CL0056/130753.html | title=关于印发《非药用类麻醉药品和精神药品列管办法》的通知 | publisher=China Food and Drug Administration | date=27 September 2015 | language=Chinese | accessdate=1 October 2015}} 4 : Cannabinoids|Designer drugs|Indoles|Indolecarboxamides |
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