词条 | 6-(2-Aminopropyl)indole |
释义 |
| IUPAC_name = 1-(1H-Indol-6-yl)propan-2-amine | image = 6-API_structure.tif | tradename = | pregnancy_category = | legal_status = Uncontrolled (but covered under the Federal Analogue Act in the United States and Australia and likely under similar bills in other countries) | routes_of_administration = Oral | bioavailability = | metabolism = | elimination_half-life = | excretion = | CAS_number = 22196-72-1 | ATC_prefix = | ATC_suffix = | PubChem = 30999 | ChemSpiderID = 28759 | C=11 | H=14 | N=2 | molecular_weight = 174.24 g/mol | smiles = C1=C2C(=CC=C1CC(C)N([H])[H])C=C[N]2[H] | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C11H14N2/c1-8(12)6-9-2-3-10-4-5-13-11(10)7-9/h2-5,7-8,13H,6,12H2,1H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = QCFIFKAOUKPFPU-UHFFFAOYSA-N }}6-(2-Aminopropyl)indole (6-API, 6-IT) is an indole derivative which was first identified being sold on the designer drug market by a laboratory in the Czech Republic in July 2016.[1] Alexander Shulgin says in his book TiHKAL "From the normal 3-position to the 2, the 4, the 5, the 6 or the 7-positions. All five alpha-methyltryptamine isomers are known, but only one is known to be active in man as a CNS active material. This is the 5-isomer, 5-(2-aminopropyl)indole or 5-IT" . Studies in dogs have also shown the drug to increase hemoglobin levels in the bloodstream.[2] Legality
References1. ^Europol 2016 Annual Report on the implementation of Council Decision 2005/387/JHA {{Entactogens|state=expanded}}{{Stimulants}}{{Adrenergics}}{{Dopaminergics}}{{Serotonergics}}{{Phenethylamines}}{{DEFAULTSORT:Aminopropyl)indole, 6-(2-}}2. ^{{cite journal|last=Maxwell|first=G. M.|title=The effects of an indole derivative 6-(2′-Aminopropyl indole) on the general and coronary haemodynamics of the intact dog|journal=Cellular and Molecular Life Sciences|year=1964|volume=20|issue=9|pages=526–527|doi=10.1007/BF02154095}} 3. ^{{cite web | url = https://www.gov.uk/government/publications/temporary-class-drug-order-report-on-benzofury-and-nbome-compounds | title = Temporary class drug order report on 5-6APB and NBOMe compounds | accessdate = 2013-07-11 | date = 4 Jun 2013 | publisher = UK Home Office}} 4. ^{{cite web | url = http://www.legislation.gov.uk/ukdsi/2014/9780111110904 | title = The Misuse of Drugs Act 1971 (Ketamine etc.) (Amendment) Order 2014 | accessdate = 2014-03-11 | author = UK Home Office | date = 2014-03-05 | publisher = UK Government}} 5. ^{{cite web | url = http://www.comlaw.gov.au/ComLaw/Legislation/ActCompilation1.nsf/0/1B4A2DD73EF9A4BBCA2576040024B600/$file/CriminalCode1995_WD02.pdf | title = Criminal Code Act 1995 | accessdate = 2012-02-08 | date = 2009-08-05 | format = PDF | publisher = Australian Government | quote = PAGE 503}} 3 : Indoles|Stimulants|Entactogens and empathogens |
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