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词条 6-Deoxy-5-ketofructose 1-phosphate synthase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = 6-deoxy-5-ketofructose 1-phosphate synthase
| EC_number = 2.2.1.11
| CAS_number =
| IUBMB_EC_number = 2/2/1/11
| GO_code =
| image =
| width =
| caption =
}}6-deoxy-5-ketofructose 1-phosphate synthase ({{EC number|2.2.1.11}}, DKFP synthase, MJ1585 (gene)) is an enzyme with systematic name 2-oxopropanal:D-fructose 1,6-bisphosphate glycerone-phosphotransferase.[1][2] This enzyme catalyses the following chemical reaction

(1) methylglyoxal + D-fructose 1,6-bisphosphate D-glyceraldehyde 3-phosphate + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate

(2) methylglyoxal + D-fructose 1-phosphate D-glyceraldehyde + 1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate

This enzyme plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate.

References

1. ^{{cite journal | vauthors = White RH, Xu H | title = Methylglyoxal is an intermediate in the biosynthesis of 6-deoxy-5-ketofructose-1-phosphate: a precursor for aromatic amino acid biosynthesis in Methanocaldococcus jannaschii | journal = Biochemistry | volume = 45 | issue = 40 | pages = 12366–79 | date = October 2006 | pmid = 17014089 | doi = 10.1021/bi061018a }}
2. ^{{cite journal | vauthors = Samland AK, Wang M, Sprenger GA | title = MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity | journal = FEMS Microbiology Letters | volume = 281 | issue = 1 | pages = 36–41 | date = April 2008 | pmid = 18318840 | doi = 10.1111/j.1574-6968.2008.01079.x }}

External links

  • {{MeshName|6-deoxy-5-ketofructose+1-phosphate+synthase}}
{{Aldehyde-ketone transferases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 2.2.1

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