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词条 6-Hydroxynicotinate 3-monooxygenase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = 6-Hydroxynicotinate 3-monooxygenase
| EC_number = 1.14.13.114
| CAS_number =
| IUBMB_EC_number = 1/14/13/114
| GO_code =
| image =
| width =
| caption =
}}6-Hydroxynicotinate 3-monooxygenase ({{EC number|1.14.13.114}}, NicC, 6HNA monooxygenase, HNA-3-monooxygenase) is an enzyme with systematic name 6-hydroxynicotinate,NADH:oxygen oxidoreductase (3-hydroxylating, decarboxylating).[1][2] This enzyme catalyses the following chemical reaction

6-hydroxynicotinate + NADH + H+ + O2 2,5-dihydroxypyridine + NAD+ + H2O + CO2

6-Hydroxynicotinate 3-monooxygenase a flavoprotein (FAD).

References

1. ^{{cite journal | vauthors = Nakano H, Wieser M, Hurh B, Kawai T, Yoshida T, Yamane T, Nagasawa T | title = Purification, characterization and gene cloning of 6-hydroxynicotinate 3-monooxygenase from Pseudomonas fluorescens TN5 | journal = European Journal of Biochemistry | volume = 260 | issue = 1 | pages = 120–6 | date = February 1999 | pmid = 10091591 | doi = 10.1046/j.1432-1327.1999.00124.x }}
2. ^{{cite journal | vauthors = Jiménez JI, Canales A, Jiménez-Barbero J, Ginalski K, Rychlewski L, García JL, Díaz E | title = Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440 | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 105 | issue = 32 | pages = 11329–34 | date = August 2008 | pmid = 18678916 | pmc = 2516282 | doi = 10.1073/pnas.0802273105 }}

External links

  • {{MeshName|6-hydroxynicotinate+3-monooxygenase}}
{{Dioxygenases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.14.13

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