“A-1,3-mannosyl-glycoprotein 4-b-N-acetylglucosaminyltransferase”的意思、由来-开放百科全书

词条

A-1,3-mannosyl-glycoprotein 4-b-N-acetylglucosaminyltransferase

释义

References
External links

{{Infobox enzyme
| Name = Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
| EC_number = 2.4.1.145
| CAS_number = 86498-16-0
| IUBMB_EC_number = 2/4/1/145
| GO_code =
| image =
| width =
| caption =
}}Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase ({{EC number|2.4.1.145}}, N-acetylglucosaminyltransferase IV, N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase IV, beta-acetylglucosaminyltransferase IV, uridine diphosphoacetylglucosamine-glycopeptide beta4-acetylglucosaminyltransferase IV, alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase, GnTIV) is an enzyme with systematic name UDP-N-acetyl-D-glucosamine:3-(2-(N-acetyl-beta-D-glucosaminyl)-alpha-D-mannosyl)-glycoprotein 4-beta-N-acetyl-D-glucosaminyltransferase.^[1] This enzyme catalyses the following chemical reaction

UDP-N-acetyl-D-glucosamine + 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R UDP + 3-(2,4-bis[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R

R represents the remainder of the N-linked oligosaccharide in the glycoprotein acceptor.

References

1. ^{{cite journal | vauthors = Gleeson PA, Schachter H | title = Control of glycoprotein synthesis | journal = The Journal of Biological Chemistry | volume = 258 | issue = 10 | pages = 6162–73 | date = May 1983 | pmid = 6222042 }}

External links

{{MeshName|Alpha-1,3-mannosyl-glycoprotein+4-beta-N-acetylglucosaminyltransferase}}

1 : EC 2.4.1

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