| 词条 | Acetylcorynoline |
| 释义 |
| ImageFile = Acetylcorynoline.svg | ImageSize = 150px | ImageAlt = | IUPACName = | OtherNames = |Section1={{Chembox Identifiers | CASNo = 18797-80-3 | PubChem = 177015 | InChI = 1S/C23H23NO6/c1-12(25)30-20-7-13-6-18-19(28-10-27-18)8-14(13)22-23(20,2)16-4-5-17-21(29-11-26-17)15(16)9-24(22)3/h4-6,8,20,22H,7,9-11H2,1-3H3/t20-,22+,23-/m0/s1 | InChIKey = PUHCFWFODBLSAP-WWNPGLIZSA-N | SMILES = CC(=O)O[C@H]1CC2=CC3=C(C=C2[C@@H]4[C@]1(C5=C(CN4C)C6=C(C=C5)OCO6)C)OCO3 | ChemSpiderID = 154160 | InChI2 = 1/C23H23NO6/c1-12(25)30-20-7-13-6-18-19(28-10-27-18)8-14(13)22-23(20,2)16-4-5-17-21(29-11-26-17)15(16)9-24(22)3/h4-6,8,20,22H,7,9-11H2,1-3H3/t20-,22+,23-/m0/s1 | InChIKey2 = PUHCFWFODBLSAP-WWNPGLIZBS |Section2={{Chembox Properties | C=23|H=23|N=1|O=6 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }}Acetylcorynoline is a bio-active isolate of Corydalis ambigua. It inhibits the maturing of bone marrow-derived dendritic cells in mice. However, it is only cytotoxic in amounts of greater than 20 μM.[1] References1. ^{{cite journal | pmid = 23472193 | year = 2013 | last1 = Fu | first1 = RH | last2 = Wang | first2 = YC | last3 = Liu | first3 = SP | last4 = Chu | first4 = CL | last5 = Tsai | first5 = RT | last6 = Ho | first6 = YC | last7 = Chang | first7 = WL | last8 = Chiu | first8 = SC | last9 = Harn | first9 = HJ | last10 = Shyu | first10 = WC | last11 = Lin | first11 = SZ | title = Acetylcorynoline impairs the maturation of mouse bone marrow-derived dendritic cells via suppression of IκB kinase and mitogen-activated protein kinase activities | volume = 8 | issue = 3 | pages = e58398 | doi = 10.1371/journal.pone.0058398 | pmc = 3589392 | journal = PLOS ONE | editor1-last = Caldwell | editor1-first = Charles C}} External links
1 : Alkaloids |
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