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词条 Acetylpropionyl
释义

  1. Safety

  2. See also

  3. References

{{Chembox
| ImageFile = Acetylpropionyl.svg
| ImageSize = 200px
| PIN = Pentane-2,3-dione
| OtherNames = 2,3-Pentanedione
|Section1={{Chembox Identifiers
| CASNo = 600-14-6
| PubChem = 11747
| ChemSpiderID = 11254
| SMILES = CCC(=O)C(=O)C
| InChI = 1/C5H8O2/c1-3-5(7)4(2)6/h3H2,1-2H3
| InChIKey = TZMFJUDUGYTVRY-UHFFFAOYAL
| StdInChI = 1S/C5H8O2/c1-3-5(7)4(2)6/h3H2,1-2H3
| StdInChIKey = TZMFJUDUGYTVRY-UHFFFAOYSA-N
|Section2={{Chembox Properties
| C=5 | H=8 | O=2
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Acetylpropionyl, also known as acetyl propionyl or 2,3-pentanedione,[1] is an organic compound, more specifically a diketone.[2]

Uses for acetylpropionyl include:

  • a solvent for cellulose acetate, paints, inks, and lacquers,
  • a starting material for dyes, pesticides, and drugs,
  • and a flavor, with an odor described as "buttery, cheesy, sweet, nutty, fruity, creamy, caramel".[3]

Safety

As a flavoring agent, it is an ingredient in some e-liquid products for use with electronic cigarettes to give a buttery or caramel flavor.[4] According to the National Institute for Occupational Safety and Health , inhalation of acetylpropionyl causes respiratory tract epithelial damage and fibrosis to lungs in animal studies. It also causes genetic changes in the animals' brains.[5]

See also

  • Diacetyl, a similar diketone

References

1. ^https://pubchem.ncbi.nlm.nih.gov/compound/2_3-pentanedione#section=Top
2. ^Hardo Siegel, Manfred Eggersdorfer "Ketones" in Ullmann's Encyclopedia of Industrial Chemistry, 2005, Wiley-VCH, Weinheim.{{DOI|10.1002/14356007.a15_077}}
3. ^http://www.chemicalland21.com/lifescience/foco/2,3-PENTANEDIONE.htm
4. ^{{cite book |chapter-url=https://www.nap.edu/read/24952/chapter/8?term=Diacetyl#175 |author1=Committee on the Review of the Health Effects of Electronic Nicotine Delivery Systems, National Academies of Sciences|editor1-last=Eaton |editor1-first=David L. |editor2-last=Kwan |editor2-first=Leslie Y. |editor3-last=Stratton |editor3-first=Kathleen |title=Public Health Consequences of E-Cigarettes |date=2018 |publisher=National Academies Press |isbn=9780309468343 |page=175 |language=en |pmid=29894118|chapter=Chapter 5: Toxicology of E-Cigarette Constituents}}
5. ^{{Cite web|title = CDC - Flavorings-Related Lung Disease: Exposures to Flavoring Chemicals - NIOSH Workplace Safety and Health Topic|url = https://www.cdc.gov/niosh/topics/flavorings/exposure.html|website = www.cdc.gov|accessdate = 2015-10-22}}

2 : Diketones|Flavors

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