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词条 Acyl-homoserine-lactone acylase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Acyl-homoserine-lactone acylase
| EC_number = 3.5.1.97
| CAS_number =
| IUBMB_EC_number = 3/5/1/97
| GO_code =
| image =
| width =
| caption =
}}Acyl-homoserine-lactone acylase ({{EC number|3.5.1.97}}, acyl-homoserine lactone acylase, AHL-acylase, AiiD, N-acyl-homoserine lactone acylase, PA2385 protein, quorum-quenching AHL acylase, quorum-quenching enzyme, PvdQ, QuiP) is an enzyme with systematic name N-acyl-L-homoserine-lactone amidohydrolase.[1][2] This enzyme functions as a quorum quencher by catalysing the following chemical reaction

an N-acyl-L-homoserine lactone + H2O L-homoserine lactone + a carboxylate

Acyl homoserine lactones (AHLs) are produced by a number of bacterial species .

References

1. ^{{cite journal | vauthors = Sio CF, Otten LG, Cool RH, Diggle SP, Braun PG, Bos R, Daykin M, Cámara M, Williams P, Quax WJ | title = Quorum quenching by an N-acyl-homoserine lactone acylase from Pseudomonas aeruginosa PAO1 | journal = Infection and Immunity | volume = 74 | issue = 3 | pages = 1673–82 | date = March 2006 | pmid = 16495538 | pmc = 1418629 | doi = 10.1128/iai.74.3.1673-1682.2006 }}
2. ^{{cite journal | vauthors = Lin YH, Xu JL, Hu J, Wang LH, Ong SL, Leadbetter JR, Zhang LH | title = Acyl-homoserine lactone acylase from Ralstonia strain XJ12B represents a novel and potent class of quorum-quenching enzymes | journal = Molecular Microbiology | volume = 47 | issue = 3 | pages = 849–60 | date = February 2003 | pmid = 12535081 | doi = 10.1046/j.1365-2958.2003.03351.x }}

External links

  • {{MeshName|Acyl-homoserine-lactone+acylase}}
{{Carbon-nitrogen non-peptide hydrolases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.5.1

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