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词条 ADAMDEC1
释义

  1. Function

  2. References

  3. Further reading

{{Orphan|date=October 2015}}

ADAM-like, decysin 1 is a protein that in humans is encoded by the ADAMDEC1 gene.

[1]

Function

This encoded protein is thought to be a secreted protein belonging to the disintegrin metalloproteinase family. Its expression is upregulated during the maturation of dendritic cells. This protein may play an important role in dendritic cell function and their interactions with germinal center T cells. [provided by RefSeq, Jul 2008].

References

1. ^{{cite web| title = Entrez Gene: ADAM-like, decysin 1| url = https://www.ncbi.nlm.nih.gov/gene/27299| accessdate = 2014-08-16 }}

Further reading

{{refbegin | 2}}
  • {{Cite journal

| pmid = 9271581
| pmc = 2199019
| year = 1997
| author1 = Mueller
| first1 = C. G.
| title = Polymerase chain reaction selects a novel disintegrin proteinase from CD40-activated germinal center dendritic cells
| journal = The Journal of Experimental Medicine
| volume = 186
| issue = 5
| pages = 655–63
| last2 = Rissoan
| first2 = M. C.
| last3 = Salinas
| first3 = B
| last4 = Ait-Yahia
| first4 = S
| last5 = Ravel
| first5 = O
| last6 = Bridon
| first6 = J. M.
| last7 = Briere
| first7 = F
| last8 = Lebecque
| first8 = S
| last9 = Liu
| first9 = Y. J.
| doi=10.1084/jem.186.5.655
}}
  • {{Cite journal

| pmid = 12037602
| year = 2002
| author1 = Bates
| first1 = E. E.
| title = The ADAMDEC1 (decysin) gene structure: Evolution by duplication in a metalloprotease gene cluster on chromosome 8p12
| journal = Immunogenetics
| volume = 54
| issue = 2
| pages = 96–105
| last2 = Fridman
| first2 = W. H.
| last3 = Mueller
| first3 = C. G.
| doi = 10.1007/s00251-002-0430-3
}}
  • {{Cite journal

| pmid = 14632642
| pmc = 1783081
| year = 2003
| author1 = Fritsche
| first1 = J
| title = Inverse regulation of the ADAM-family members, decysin and MADDAM/ADAM19 during monocyte differentiation
| journal = Immunology
| volume = 110
| issue = 4
| pages = 450–7
| last2 = Müller
| first2 = A
| last3 = Hausmann
| first3 = M
| last4 = Rogler
| first4 = G
| last5 = Andreesen
| first5 = R
| last6 = Kreutz
| first6 = M
| doi=10.1111/j.1365-2567.2003.01754.x
}}
  • {{Cite journal

| pmid = 19218196
| pmc = 2684019
| year = 2009
| author1 = Crouser
| first1 = E. D.
| title = Gene expression profiling identifies MMP-12 and ADAMDEC1 as potential pathogenic mediators of pulmonary sarcoidosis
| journal = American Journal of Respiratory and Critical Care Medicine
| volume = 179
| issue = 10
| pages = 929–38
| last2 = Culver
| first2 = D. A.
| last3 = Knox
| first3 = K. S.
| last4 = Julian
| first4 = M. W.
| last5 = Shao
| first5 = G
| last6 = Abraham
| first6 = S
| last7 = Liyanarachchi
| first7 = S
| last8 = Macre
| first8 = J. E.
| last9 = Wewers
| first9 = M. D.
| last10 = Gavrilin
| first10 = M. A.
| last11 = Ross
| first11 = P
| last12 = Abbas
| first12 = A
| last13 = Eng
| first13 = C
| doi = 10.1164/rccm.200803-490OC
}}
  • {{Cite journal

| pmid = 11673514
| year = 2001
| author1 = Mueller
| first1 = C. G.
| title = Mannose receptor ligand-positive cells express the metalloprotease decysin in the B cell follicle
| journal = Journal of Immunology
| volume = 167
| issue = 9
| pages = 5052–60
| last2 = Cremer
| first2 = I
| last3 = Paulet
| first3 = P. E.
| last4 = Niida
| first4 = S
| last5 = Maeda
| first5 = N
| last6 = Lebeque
| first6 = S
| last7 = Fridman
| first7 = W. H.
| last8 = Sautès-Fridman
| first8 = C
| doi=10.4049/jimmunol.167.9.5052
}}
  • {{Cite journal

| pmid = 18449420
| year = 2008
| author1 = Berger
| first1 = M
| title = Association of ADAMDEC1 haplotype with high factor VIII levels in venous thromboembolism
| journal = Thrombosis and Haemostasis
| volume = 99
| issue = 5
| pages = 905–8
| last2 = Moscatelli
| first2 = H
| last3 = Kulle
| first3 = B
| last4 = Luxembourg
| first4 = B
| last5 = Blouin
| first5 = K
| last6 = Spannagl
| first6 = M
| last7 = Lindhoff-Last
| first7 = E
| last8 = Schambeck
| first8 = C. M.
| doi = 10.1160/TH08-01-0059
}}{{refend}}{{NLM content}}{{Metalloendopeptidases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{gene-8-stub}}

2 : Peptidase|EC 3.4.24

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