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词条 ADP-dependent NAD(P)H-hydrate dehydratase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = ADP-dependent NAD(P)H-hydrate dehydratase
| EC_number = 4.2.1.136
| CAS_number =
| IUBMB_EC_number = 4/2/1/136
| GO_code =
| image =
| width =
| caption =
}}ADP-dependent NAD(P)H-hydrate dehydratase ({{EC number|4.2.1.136}}, (6S)-beta-6-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing), (6S)-6-beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing, NADH-forming)) is an enzyme with systematic name (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine-dinucleotide hydro-lyase (ADP-hydrolysing; NADH-forming).[1] This enzyme catalyses the following chemical reaction

(1) ADP + (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide AMP + phosphate + NADH

(2) ADP + (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide-adenine dinucleotide phosphate AMP + phosphate + NADPH

This enzyme acts equally well on hydrated NADH and hydrated NADPH.

References

1. ^{{cite journal | vauthors = Marbaix AY, Noël G, Detroux AM, Vertommen D, Van Schaftingen E, Linster CL | title = Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair | journal = The Journal of Biological Chemistry | volume = 286 | issue = 48 | pages = 41246–52 | date = December 2011 | pmid = 21994945 | pmc = 3308837 | doi = 10.1074/jbc.c111.310847 }}

External links

  • {{MeshName|ADP-dependent+NAD(P)H-hydrate+dehydratase}}
{{Carbon-oxygen lyases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 4.2.1

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