| 词条 | Aerococcus urinae |
| 释义 |
| image = Aerococcus urinae - colonies.jpg | image_alt = | image_caption = Aerococcus urinae on blood agar, showing alpha hemolytic colonies.[1] | image2 = Aerococcus urinae - microscopy.jpg | image2_alt = | image2_caption = Microscopy of Aerococcus urinae with gram stain, showing gram positive cocci.[1] | domain = Bacteria | phylum = Firmicutes | classis = Bacilli | ordo = Lactobacillales | familia = Aerococcaceae | genus = Aerococcus | species = A. urinae | binomial = Aerococcus urinae | binomial_authority = }} ClassificationAerococcus urinae is a member of the bacterial genus Aerococcus. The bacterium is a Gram-positive, catalase-negative coccus growing in clusters. Isolates of this genus were originally isolated in 1953 from samples collected in the air and dust of occupied rooms and were distinguished by their tetrad cellular arrangements.[2] Later, it was found in the urine of patients with urinary tract infections[3] and in 1992, A. urinae was assigned as distinct species.[4] Due to difficulties in the biochemical identification of A. urinae in clinical microbiological laboratories, the incidence of infections with this bacterium has likely been underestimated and secure identification relies on genetic techniques like 16S ribosomal subunit sequencing or mass spectroscopic methods such as MALDI-TOF.[5]Clinical relevanceA. urinae may also cause invasive infections including urosepsis and infective endocarditis, especially in elderly men with underlying urinary tract diseases.[6][7]A. urinae is sensitive to many commonly used antibiotics such as penicillin, cephalosporins, and vancomycin. However, the bacterium is often resistant to many antibiotics used in urinary tract infections such as sulfamethoxazole, trimethoprim and ciprofloxacin.[8] Nitrofurantoin has been reported to be effective in one series of 42 clinical isolates.[9] The bacterium can form biofilms on foreign materials and can aggregate human platelets, two features of potential importance for the disease causing capacity of this organism.[10]A. urinae is the most common aerococcus isolated from invasive human infections whereas Aerococcus sanguinicola is isolated from human urine as often as A. urinae.[11]References1. ^1 {{cite journal|last1=Mattila|first1=Jonatan|last2=Häggström|first2=Mikael|title=Images of Aerococcus urinae|journal=WikiJournal of Medicine|date=2015|volume=2|issue=1|doi=10.15347/wjm/2015.001}} 2. ^{{Cite journal|title = Aerococcus, a New Bacterial Genus|journal = Journal of General Microbiology|date = 1953-06-01|pages = 475–480|volume = 8|issue = 3|doi = 10.1099/00221287-8-3-475|pmid = 13061751|first = R. E. O.|last = Williams|first2 = A.|last2 = Hirch|first3 = S. T.|last3 = Cowan}} 3. ^{{cite journal|last=Christensen|first=JJ|author2=Vibits, H|author3= Ursing, J|author4= Korner, B|title=Aerococcus-like organism, a newly recognized potential urinary tract pathogen.|journal=Journal of Clinical Microbiology|date=May 1991|volume=29|issue=5|pages=1049–53|pmid=2056040|pmc=269932}} 4. ^{{cite journal|last=Aguirre|first=M.|author2=Collins, M. D.|title=Phylogenetic analysis of some Aerococcus-like organisms from urinary tract infections: description of Aerococcus urinae sp. nov.|journal=Journal of General Microbiology|date=1 February 1992|volume=138|issue=2|pages=401–405|doi=10.1099/00221287-138-2-401|pmid=1373437}} 5. ^{{cite journal|last=Rasmussen|first=M|title=Aerococci and aerococcal infections.|journal=Journal of Infection|date=December 2012|doi=10.1016/j.jinf.2012.12.006|pmid=23277106|volume=66|issue=6|pages=467–74}} 6. ^{{cite journal|last=Ebnöther|first=C|author2=Altwegg, M|author3= Gottschalk, J|author4= Seebach, JD|author5= Kronenberg, A|title=Aerococcus urinae endocarditis: case report and review of the literature.|journal=Infection|date=Oct 2002|volume=30|issue=5|pages=310–3|pmid=12382093|doi=10.1007/s15010-002-3106-x}} 7. ^{{cite journal|last=Senneby|first=E|author2=Petersson, A-C|author3= Rasmussen, M|title=Clinical and microbiological features of bacteremia with Aerococcus urinae.|journal=Clinical Microbiology and Infection|date=June 2012|volume=18|issue=6|pages=546–50|doi= 10.1111/j.1469-0691.2011.03609.x|pmid=21895858}} 8. ^{{cite journal|last=Rasmussen|first=M|title=Aerococci and aerococcal infections.|journal=Journal of Infection|date=June 2013|volume=66|issue=6|pages=467–74|doi= 10.1128/JCM.02637-12|pmid=23390276|pmc=3666765}} 9. ^{{Cite journal|title = Urinary tract infections withAerococcus urinae in the South of the Netherlands|journal = European Journal of Clinical Microbiology and Infectious Diseases|date = 1997-12-01|issn = 0934-9723|pages = 871–875|volume = 16|issue = 12|doi = 10.1007/BF01700552|language = en|first = P. M. H.|last = Schuur|first2 = M. E. E. v|last2 = Kasteren|first3 = L.|last3 = Sabbe|first4 = M. C.|last4 = Vos|first5 = M. M. P. C.|last5 = Janssens|first6 = A. G. M.|last6 = Buiting}} 10. ^{{cite journal|last=Shannon|first=O|author2=Mörgelin, M|author3= Rasmussen, M|title=Platelet activation and biofilm formation by Aerococcus urinae, an endocarditis-causing pathogen.|journal=Infection and Immunity|date=Oct 2010|volume=78|issue=10|pages=4268–75|doi= 10.1128/IAI.00469-10|pmid=20696834|pmc=2950351}} 11. ^{{cite journal|last=Senneby|first=E|author2=Petersson, A-C|author3= Rasmussen, M|title=Epidemiology and antibiotic susceptibility of aerococci in urinary cultures..|journal=Diagn Microbiol Infect Dis.|date=Nov 2014 }} External links
2 : Wikipedia articles with sections published in WikiJournal of Medicine|Lactobacillales |
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