AFSP may refer to:

• Annual Filing Season Program, the United States IRS continuing education program for tax return preparers
• American Foundation for Suicide Prevention

• Book:Dropkick Murphys
• Book:Drum kit
• Book:Dubnium
• Book:Dugway Proving Ground
• Book:Dugway Proving Ground - Recommended Reading
• Book:Duke Nukem series
• Book:Duran Duran
• Book:Dysprosium
• Book:Early Inhabitants in the British Isles
• Book:Early Tours
• Book:EarthBound series
• Book:Earth science
• Book:Easy to Understand Chemistry
• Book:Economics
• Book:Economic Statistics
• Booked Out
• Booked! (radio show)
• Book:Education
• Bookeen
• Book:Einsteinium
• Book:Ekaterina II-class battleships
• Book:ELearning
• Book:E-learning
• Book:Electric Light Orchestra
• Book:Electronic structure methods