词条 | Alafosfalin |
释义 |
| ImageFile = Alafosfalin.svg | ImageAlt = | IUPACName = ((1R)-1-(((2S)-2-aminopropanoyl)amino]ethyl)phosphonic acid | OtherNames = |Section1={{Chembox Identifiers | CASNo = 60668-24-8 | PubChem = 71957 | SMILES = C[C@@H](C(=O)N[C@@H](C)P(=O)(O)O)N | ChemSpiderID = 64964 | InChI = 1/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1 | InChIKey = BHAYDBSYOBONRV-IUYQGCFVBQ | StdInChI = 1S/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1 | StdInChIKey = BHAYDBSYOBONRV-IUYQGCFVSA-N}} |Section2={{Chembox Properties | Formula = C5H13N2O4P | MolarMass = 196.14 g/mol | Appearance = | Density = | MeltingPtC = 295-297 | MeltingPt_notes = (decomp) | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }} Alafosfalin is an phosphonodipeptide with antibacterial[1] and antifungal[2] properties. References1. ^{{cite journal|last1=Atherton|first1=Frank R.|last2=Hassall|first2=Cedric H.|last3=Lambert|first3=Robert W.|title=Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid|journal=Journal of Medicinal Chemistry|date=January 1986|volume=29|issue=1|pages=29–40|doi=10.1021/jm00151a005}} {{organic-chem-stub}}2. ^{{cite journal|last1=Khomutov|first1=Radii M.|last2=Osipova|first2=Tatyana I.|last3=Khurs|first3=Elena N.|last4=Dzhavakhiya|first4=Vitalii G.|title=Synthesis of alafosfalin and its phosphinic analogue and their fungicidal activity|journal=Mendeleev Communications|date=November 2008|volume=18|issue=6|pages=295–296|doi=10.1016/j.mencom.2008.11.001}} 1 : Dipeptides |
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