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词条 Alafosfalin
释义

  1. References

{{Chembox
| ImageFile = Alafosfalin.svg
| ImageAlt =
| IUPACName = ((1R)-1-(((2S)-2-aminopropanoyl)amino]ethyl)phosphonic acid
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo = 60668-24-8
| PubChem = 71957
| SMILES = C[C@@H](C(=O)N[C@@H](C)P(=O)(O)O)N
| ChemSpiderID = 64964
| InChI = 1/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1
| InChIKey = BHAYDBSYOBONRV-IUYQGCFVBQ
| StdInChI = 1S/C5H13N2O4P/c1-3(6)5(8)7-4(2)12(9,10)11/h3-4H,6H2,1-2H3,(H,7,8)(H2,9,10,11)/t3-,4+/m0/s1
| StdInChIKey = BHAYDBSYOBONRV-IUYQGCFVSA-N}}
|Section2={{Chembox Properties
| Formula = C5H13N2O4P
| MolarMass = 196.14 g/mol
| Appearance =
| Density =
| MeltingPtC = 295-297
| MeltingPt_notes = (decomp)
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}

Alafosfalin is an phosphonodipeptide with antibacterial[1] and antifungal[2] properties.

References

1. ^{{cite journal|last1=Atherton|first1=Frank R.|last2=Hassall|first2=Cedric H.|last3=Lambert|first3=Robert W.|title=Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid|journal=Journal of Medicinal Chemistry|date=January 1986|volume=29|issue=1|pages=29–40|doi=10.1021/jm00151a005}}
2. ^{{cite journal|last1=Khomutov|first1=Radii M.|last2=Osipova|first2=Tatyana I.|last3=Khurs|first3=Elena N.|last4=Dzhavakhiya|first4=Vitalii G.|title=Synthesis of alafosfalin and its phosphinic analogue and their fungicidal activity|journal=Mendeleev Communications|date=November 2008|volume=18|issue=6|pages=295–296|doi=10.1016/j.mencom.2008.11.001}}
{{organic-chem-stub}}

1 : Dipeptides

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