| 词条 | Albumin I |
| 释义 |
| Symbol = Albumin_I | Name = Albumin_I | image = PDB 1p8b EBI.jpg | width = | caption = Solution structure of PA1b. PDB entry {{PDBe|1p8b}}[1] | Pfam = PF08027 | Pfam_clan = CL0083 | InterPro = IPR012512 | SMART = | PROSITE = | MEROPS = | SCOP = | TCDB = | OPM family = | OPM protein = | CAZy = | CDD = }}Albumin I (PA1b) is a hormone-like peptide found in the seeds of legumes such as the pea plant (Pisum sativum)[2] or soya bean (Glycine max)[3] which have been shown to have insecticidal properties.[2] It stimulates kinase activity upon binding a membrane bound 43 kDa receptor within the plant which affects cell proliferation.[3] The structure reveals an inhibitor cystine knot (knottin)-like fold, comprising three beta strands.[1][2] References1. ^1 {{Cite journal | last1 = Jouvensal | first1 = L. | last2 = Quillien | first2 = L. | last3 = Ferrasson | first3 = E. | last4 = Rahbé | first4 = Y. | last5 = Guéguen | first5 = J. | last6 = Vovelle | first6 = F. O. | doi = 10.1021/bi034803l | title = PA1b, an Insecticidal Protein Extracted from Pea Seeds (Pisum sativum): 1H-2-D NMR Study and Molecular Modeling†,‡ | journal = Biochemistry | volume = 42 | issue = 41 | pages = 11915–11923 | year = 2003 | pmid = 14556622 | pmc = }} {{InterPro content|IPR012512}}2. ^1 2 {{Cite journal | last1 = Da Silva | first1 = P. | last2 = Rahioui | first2 = I. | last3 = Laugier | first3 = C. | last4 = Jouvensal | first4 = L. | last5 = Meudal | first5 = H. | last6 = Chouabe | first6 = C. | last7 = Delmas | first7 = A. F. | last8 = Gressent | first8 = F. | doi = 10.1074/jbc.M110.147199 | title = Molecular Requirements for the Insecticidal Activity of the Plant Peptide Pea Albumin 1 Subunit b (PA1b) | journal = Journal of Biological Chemistry | volume = 285 | issue = 43 | pages = 32689–32694 | year = 2010 | pmid = 20660598 | pmc =2963353 }} 3. ^1 {{cite journal |vauthors=Yamazaki T, Takaoka M, Katoh E, Hanada K, Sakita M, Sakata K, Nishiuchi Y, Hirano H | title = A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes | journal = Eur. J. Biochem. | volume = 270 | issue = 6 | pages = 1269–76 |date=March 2003 | pmid = 12631285 | doi = 10.1046/j.1432-1033.2003.03489.x| url = }} 1 : Protein domains |
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