词条 | Aldos-2-ulose dehydratase |
释义 |
| Name = Aldos-2-ulose dehydratase | EC_number = 4.2.1.110 | CAS_number = 101920-80-3 | IUBMB_EC_number = 4/2/1/110 | GO_code = | image = | width = | caption = }}Aldos-2-ulose dehydratase ({{EC number|4.2.1.110}}, pyranosone dehydratase, AUDH, 1,5-anhydro-D-fructose dehydratase (microthecin-forming)) is an enzyme with systematic name 1,5-anhydro-D-fructose hydro-lyase (microthecin-forming).[1][2][3][4][5] This enzyme catalyses the following chemical reaction 1,5-anhydro-D-fructose 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O (overall reaction) (1a) 1,5-anhydro-D-fructose 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one This enzyme catalyses two of the steps in the anhydrofructose pathway. References1. ^{{cite journal | vauthors = Yu S, Fiskesund R | title = The anhydrofructose pathway and its possible role in stress response and signaling | journal = Biochimica et Biophysica Acta | volume = 1760 | issue = 9 | pages = 1314–22 | date = September 2006 | pmid = 16822618 | doi = 10.1016/j.bbagen.2006.05.007 }} 2. ^{{cite journal | vauthors = Yu S | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate | journal = Biochimica et Biophysica Acta | volume = 1723 | issue = 1-3 | pages = 63–73 | date = May 2005 | pmid = 15716041 | doi = 10.1016/j.bbagen.2005.01.004 }} 3. ^{{cite journal | title = Presence of microthecin in the red alga Gracilariopsis lemaneiformis and its formation from 1,5-anhydro-D-fructose |author1 = Broberg, A. |author2 =Kenne, L. |author3 =Pedersén, M. |journal = Phytochemistry |year = 1996 |volume = 41 |pages = 151–154 |pmid = |doi=10.1016/0031-9422(95)00587-0}} 4. ^{{cite journal | vauthors = Gabriel J, Volc J, Sedmera P, Daniel G, Kubátová E | title = Pyranosone dehydratase from the basidiomycete Phanerochaete chrysosporium: improved purification, and identification of 6-deoxy-D-glucosone and D-xylosone reaction products | journal = Archives of Microbiology | volume = 160 | issue = 1 | pages = 27–34 | year = 1993 | pmid = 8352649 | doi = 10.1007/BF00258142 }} 5. ^{{cite journal | vauthors = Yu S, Refdahl C, Lundt I | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma | journal = Biochimica et Biophysica Acta | volume = 1672 | issue = 2 | pages = 120–9 | date = May 2004 | pmid = 15110094 | doi = 10.1016/j.bbagen.2004.03.004 }} External links
1 : EC 4.2.1 |
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