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词条 Aldos-2-ulose dehydratase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Aldos-2-ulose dehydratase
| EC_number = 4.2.1.110
| CAS_number = 101920-80-3
| IUBMB_EC_number = 4/2/1/110
| GO_code =
| image =
| width =
| caption =
}}Aldos-2-ulose dehydratase ({{EC number|4.2.1.110}}, pyranosone dehydratase, AUDH, 1,5-anhydro-D-fructose dehydratase (microthecin-forming)) is an enzyme with systematic name 1,5-anhydro-D-fructose hydro-lyase (microthecin-forming).[1][2][3][4][5] This enzyme catalyses the following chemical reaction

1,5-anhydro-D-fructose 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O (overall reaction)

(1a) 1,5-anhydro-D-fructose 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O

(1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one

This enzyme catalyses two of the steps in the anhydrofructose pathway.

References

1. ^{{cite journal | vauthors = Yu S, Fiskesund R | title = The anhydrofructose pathway and its possible role in stress response and signaling | journal = Biochimica et Biophysica Acta | volume = 1760 | issue = 9 | pages = 1314–22 | date = September 2006 | pmid = 16822618 | doi = 10.1016/j.bbagen.2006.05.007 }}
2. ^{{cite journal | vauthors = Yu S | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation II. Gene identification and characterization of the reactions catalyzed by aldos-2-ulose dehydratase that converts 1,5-anhydro-D-fructose to microthecin with ascopyrone M as the intermediate | journal = Biochimica et Biophysica Acta | volume = 1723 | issue = 1-3 | pages = 63–73 | date = May 2005 | pmid = 15716041 | doi = 10.1016/j.bbagen.2005.01.004 }}
3. ^{{cite journal | title = Presence of microthecin in the red alga Gracilariopsis lemaneiformis and its formation from 1,5-anhydro-D-fructose |author1 = Broberg, A. |author2 =Kenne, L. |author3 =Pedersén, M. |journal = Phytochemistry |year = 1996 |volume = 41 |pages = 151–154 |pmid = |doi=10.1016/0031-9422(95)00587-0}}
4. ^{{cite journal | vauthors = Gabriel J, Volc J, Sedmera P, Daniel G, Kubátová E | title = Pyranosone dehydratase from the basidiomycete Phanerochaete chrysosporium: improved purification, and identification of 6-deoxy-D-glucosone and D-xylosone reaction products | journal = Archives of Microbiology | volume = 160 | issue = 1 | pages = 27–34 | year = 1993 | pmid = 8352649 | doi = 10.1007/BF00258142 }}
5. ^{{cite journal | vauthors = Yu S, Refdahl C, Lundt I | title = Enzymatic description of the anhydrofructose pathway of glycogen degradation; I. Identification and purification of anhydrofructose dehydratase, ascopyrone tautomerase and alpha-1,4-glucan lyase in the fungus Anthracobia melaloma | journal = Biochimica et Biophysica Acta | volume = 1672 | issue = 2 | pages = 120–9 | date = May 2004 | pmid = 15110094 | doi = 10.1016/j.bbagen.2004.03.004 }}

External links

  • {{MeshName|Aldos-2-ulose+dehydratase}}
{{Carbon-oxygen lyases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 4.2.1

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