“Alexander Klibanov (biologist)”的意思、由来-开放百科全书

词条

Alexander Klibanov (biologist)

释义

Targeted microbubbles
References
Sources

{{Infobox scientist
|birth_name =
|image =
|caption =
|birth_date =
|birth_place =
|nationality =
|fields = {{Plainlist|

Biochemistry
Molecular Imaging
Medical ultrasonography

}}
|workplaces ={{Plainlist|

University of Virginia

}}
|alma_mater = {{Plainlist|

Russian Academy of Medical Sciences

}}
|doctoral_advisor =
|academic_advisors =
|doctoral_students =
|notable_students =
|known_for = Targeted contrast media for molecular ultrasonography
|influences =
|influenced =
| awards = {{Plainlist|

Lenin Komsomol Prize (1988)
— co-laureate

}}
|signature =
}}

Alexander L. (Sasha) Klibanov ({{lang-rus|Александр Л. Клибанов}}) is Associate Professor in the Division of Cardiovascular Medicine and Department of Biomedical Engineering at the University of Virginia. He specializes in the study of ultrasound and medical imaging techniques.

Targeted microbubbles

Dr. Klibanov designed targeted microbubbles in 1997 ^[1] that launched a new medical imaging modality, named molecular ultrasonography or ultrasound molecular imaging.^[2] Potential clinical applications are expected in cancer screening to detect malignant tumors at their earliest stage of appearance; with intravenous injection of targeted microbubbles that specifically bind to tumoral microvessels by targeting biomolecular cancer expression (overexpression of certain biomolecules occurs during neo-angiogenesis or inflammation processes).

References

1. ^{{cite journal |pmid=9240089 |year=1997|last1=Klibanov|first1=A. L. |last2=Hughes |first2=M. S. |last3=Marsh |first3=J. N. |last4=Hall |first4=C. S. |last5=Miller |first5=J. G. |last6=Wilble |first6=J. H. |last7=Brandenburger |first7=G. H. |title=Targeting of ultrasound contrast material. An in vitro feasibility study |volume=412 |issue= |pages=113–120 |doi=|journal=Acta Radiologica Supplementum}}
2. ^{{cite journal |doi=10.1016/S0169-409X(98)00104-5 |title=Targeted delivery of gas-filled microspheres, contrast agents for ultrasound imaging |year=1999 |last1=Klibanov |first1=A |journal=Advanced Drug Delivery Reviews |volume=37 |pages=139–157 |pmid=10837732 |issue=1–3}}

Sources

University of Virginia bio page of Kilbanov

3 : University of Virginia School of Medicine faculty|Living people|Year of birth missing (living people)

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。