| 词条 | Alexandra Worden |
| 释义 |
| name = Alexandra Zoe Worden | image = AlexandraWorden 2017.jpg | image_size = | caption = Alexandra Z. Worden in 2017 | birth_place = Middlesex County, Massachusetts, United States | residence = Santa Cruz, California, United States | nationality = American | field = Microbiology, Oceanography | work_institution = Monterey Bay Aquarium Research Institute | doctoral_advisor = Brian Binder | known_for = work on Biogeochemical cycling, Evolutionary biology }} Alexandra (Alex) Z. Worden (born 1970) is a marine microbial ecologist and genome scientist. She leads the microbial ecology research group at the Monterey Bay Aquarium Research Institute where she holds the position of Senior Scientist. Her laboratory also bridges with the Ocean Sciences Department at the University of California Santa Cruz where she is Professor Adjunct. Worden’s research focuses on the physiology and ecology of eukaryotic phytoplankton, unicellular organisms that are responsible for a large portion of ocean primary production (photosynthetic uptake of atmospheric carbon dioxide). Worden’s early work focused on methods development for directly investigating populations in the nature environment and their roles in the carbon cycle.[1][2] This theme has persisted throughout her research career. As a postdoctoral fellow at Scripps Institution of Oceanography Worden was recognized for establishing the importance of small eukaryotic phytoplankton known as picoeukaryotes.[3][4] A second study by Worden while in the laboratory of Farooq Azam overturned the idea that Vibrio cholerae existed primarily attached to copepods in aquatic systems.[5] This was considered important for understanding ecology of this human pathogen and vectors for transmission of infective cells. She and Azam also introduced the concept of Ecosystems Biology (also spelled Eco-systems Biology or (Eco)-systems Biology), coining the term in a 2004 perspective.[6] The concept was embraced by the scientific community in several later perspectives,[7][8] and is being pursued by human microbiome-biologist Jeroen Raes and microbial oceanographer Edward DeLong. A Jacques Monod conference on Marine Eco-Systems Biology was initiated in 2015.[9] Worden pioneered eukaryotic "targeted metagenomics" [10][11][12] wherein cells of particular interest are separated from the masses using flow cytometry (on a ship) and genomes are then sequenced from only the cells of greatest interest. Using this approach Worden and collaborators at the DOE Joint Genome Institute sequenced partial genomes from uncultured eukaryotic algae whilst showing the distribution of these photosynthetic protists in the ocean. Her laboratory also investigates ancestral components of land plants,[13] evolutionary biology and distributions of uncultured taxa[14][15] and interactions between viruses and phytoplankton host cells. In 2015, she and co-authors called for a "rethinking of the marine carbon cycle".[16] Worden publishes in the fields of environmental microbiology, evolutionary biology, genome science and oceanography. She is a proponent of STEM education and innovation and has highlighted the need for relevant "...role models to inspire greater diversity and creativity" in science.[17] CareerWorden started her laboratory in 2004 as Assistant Professor at the Rosenstiel School of Marine and Atmospheric Science in Miami, Florida USA. In 2004 she was also awarded a Young Investigator in [https://www.moore.org/initiative-strategy-detail?initiativeId=marine-microbiology-initiative Marine Microbiology] Award[18] by the Gordon and Betty Moore Foundation. In 2007 she was hired to build a microbial ecology research group at MBARI on the U.S. West Coast under the leadership of Marcia McNutt. In 2009, Worden was named a scholar of the Canadian Institute for Advanced Research (CIFAR), later becoming a fellow of CIFAR (2011). She became a GBMF Marine Investigator in 2013, an award given for her "creativity, innovation, and potential to make major, new breakthroughs"[19] and was elected as a Fellow of the American Academy of Microbiology in 2016.[20] EducationWorden attended Wellesley College, where she received a B.A. in history, and performed a concentration in Earth, Atmospheric and Planetary Sciences coursework at the Massachusetts Institute of Technology. At the latter she worked in the laboratories of John M. Edmond,[21] Reginald Newell and Sallie W. Chisholm. Worden received her Ph.D. from the Odum School of Ecology in 2000. Engineering is a component of her oceanographic research. Worden's initial engineering exposure was through computer programming and work after high school at BBN Technologies and with the MIT solar electric car project. The team included several individuals who leading innovators in the tech world, including Gill Pratt[22] and Megan Smith, and was led by her brother James Worden.[23][24][25] FamilyWorden has a partner and two children.[26][27] See also
References1. ^{{cite web|url=http://cordis.europa.eu/fetch?CALLER=EN_NEWS&ACTION=D&SESSION=&RCN=30681|title=European Commission : CORDIS : News and Events : Green genes provide insights into climate change|website=cordis.europa.eu}} {{refbegin}}{{refend}}2. ^{{cite web|url=https://www.youtube.com/watch?v=a7kY4GQAgIg|title=JGI Community Faces: Alexandra Z. Worden|last=DOE Joint Genome Institute|date=16 October 2008|publisher=|via=YouTube}} 3. ^{{cite journal|doi=10.4319/lo.2004.49.1.0168 | volume=49 | issue=1 | title=Assessing the dynamics and ecology of marine picophytoplankton: The importance of the eukaryotic component | journal=Limnology and Oceanography | pages=168–179 | author=Worden Alexandra Z| citeseerx=10.1.1.527.5206 | year=2004 }} 4. ^{{cite web |url=http://www.cell.com/current-biology/pdf/S0960-9822(15)00324-3.pdf |title=Research |website=cell.com}} 5. ^{{cite journal |vauthors=Worden AZ, Seidel M, Smriga S, Wick A, Malfatti F, Bartlett D, Azam F | year = 2006 | title = Trophic regulation of Vibrio cholerae in coastal marine waters | journal = Environmental Microbiology | volume = 8 | pages = 21–29 | pmid = 16343318 | doi=10.1111/j.1462-2920.2005.00863.x | issue=1}} 6. ^{{cite journal|pmid=15016987|year=2004|author1=Azam|first1=F|title=Oceanography. Microbes, molecules, and marine ecosystems|journal=Science|volume=303|issue=5664|pages=1622–4|last2=Worden|first2=A. Z.|doi=10.1126/science.1093892}} 7. ^{{cite journal|pmid=18587409|year=2008|author1=Raes|first1=J|title=Molecular eco-systems biology: Towards an understanding of community function|journal=Nature Reviews Microbiology|volume=6|issue=9|pages=693–9|last2=Bork|first2=P|doi=10.1038/nrmicro1935}} 8. ^{{cite journal |pmc=3196472|year=2011|author1=Karsenti|first1=E|title=A Holistic Approach to Marine Eco-Systems Biology|journal=PLoS Biology|volume=9|issue=10|pages=e1001177|last2=Acinas|first2=S. G.|last3=Bork|first3=P|last4=Bowler|first4=C|last5=De Vargas|first5=C|last6=Raes|first6=J|last7=Sullivan|first7=M|last8=Arendt|first8=D|last9=Benzoni|first9=F|last10=Claverie|first10=J. 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Z.|title=Environmental science. Rethinking the marine carbon cycle: Factoring in the multifarious lifestyles of microbes|journal=Science|volume=347|issue=6223|pages=1257594|last2=Follows|first2=M. J.|last3=Giovannoni|first3=S. J.|last4=Wilken|first4=S|last5=Zimmerman|first5=A. E.|last6=Keeling|first6=P. J.|doi=10.1126/science.1257594}} 17. ^{{cite web|url=http://www.tos.org/oceanography/issue/volume-27-issue-04-supplement|title=Volume 27 Issue 04 Supplement - Oceanography|website=www.tos.org}} 18. ^http://aslo.org/bulletin/04_v13_i4.pdf ASLO Bulletin Vol 13 (4) December 2004 19. ^{{cite web|url=http://goodtimes.sc/uncategorized/mini-microbes-make-a-big-splash/|title=Mini Microbes Make A Big Splash - Good Times Santa Cruz|website=goodtimes.sc|date=2013-02-13}} 20. ^{{cite web|url=https://www.asm.org/index.php/asm-newsroom2/press-releases/94046-78-fellows-elected-to-the-american-academy-of-microbiology|title=78 Fellows Elected to the American Academy of Microbiology|first=Joanna|last=Urban|website=www.asm.org}} 21. ^{{cite web|url=http://web.mit.edu/12.000/www/m2005/a2/finalwebsite/environ/locale/jedmond.shtml|title=JOHN EDMOND|website=web.mit.edu}} 22. ^{{cite web|url=http://spectrum.ieee.org/automaton/robotics/artificial-intelligence/gill-pratt-on-toyota-robot-plans|title=Gill Pratt Discusses Toyota's AI Plans and the Future of Robots and Cars|website=IEEE Spectrum: Technology, Engineering, and Science News|year=2015}} 23. ^{{cite news|url=https://www.nytimes.com/1994/03/06/business/profile-in-quest-for-electric-cars-he-adds-the-power-of-faith.html?pagewanted=all|title=Profile; In Quest for Electric Cars, He Adds the Power of Faith|first=Matthew L.|last=Wald|newspaper=The New York Times|date=1994-03-06}} 24. ^{{cite web|url=https://babelniche.wordpress.com/2014/07/28/solectria-achieving-goals-by-lowering-them/|title=Solectria – Achieving Goals By Lowering Them|date=28 July 2014|website=wordpress.com}} 25. ^{{cite web|url=http://tech.mit.edu/V111/N19/solar.19s.html|title=Solar car sets world record - The Tech|website=tech.mit.edu}} 26. ^{{cite web|url=https://www.aaas.org/blog/member-spotlight/alexandra-worden-and-eukaryote-tree-life|title=Alexandra Worden and the eukaryote tree of life|date=10 June 2016|website=aaas.org}} 27. ^{{cite web |url=https://www.asm.org/index.php/aam-fellows/news-views/interviews-with-fellows/item/6811-alexandra-z-worden |title=Bio|website=asm.org}} External links
10 : American microbiologists|Science teachers|Living people|1970 births|Women microbiologists|American women scientists|21st-century women scientists|University of California, Santa Cruz faculty|Wellesley College alumni|University of Georgia alumni |
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