词条 | Alpha-Chlorocodide |
释义 |
| Name = α-Chlorocodide | ImageFile = Alpha-Chlorocodide.svg | ImageSize = 180px | IUPACName = (5α,6β)-6-Chloro-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan | OtherNames = |Section1={{Chembox Identifiers | CASNo = | PubChem = 5486612 | ChemSpiderID = 4588984 | SMILES = Cl[C@@H]2\\C=C/[C@H]5[C@@H]4N(CC[C@@]51c3c(O[C@H]12)c(OC)ccc3C4)C | InChI = 1/C18H20ClNO2/c1-20-8-7-18-11-4-5-12(19)17(18)22-16-14(21-2)6-3-10(15(16)18)9-13(11)20/h3-6,11-13,17H,7-9H2,1-2H3/t11-,12+,13+,17-,18-/m0/s1 | InChIKey = CVLHOXTTXWEUCL-KEMUOJQUBZ | StdInChI = 1S/C18H20ClNO2/c1-20-8-7-18-11-4-5-12(19)17(18)22-16-14(21-2)6-3-10(15(16)18)9-13(11)20/h3-6,11-13,17H,7-9H2,1-2H3/t11-,12+,13+,17-,18-/m0/s1 | StdInChIKey = CVLHOXTTXWEUCL-KEMUOJQUSA-N |Section2={{Chembox Properties | C=18 | H=20 | Cl=1 | N=1 | O=2 | Appearance = | Density = | MeltingPtC = 151 to 154 | MeltingPt_ref = [1] | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} α-Chlorocodide is an opioid analog that is a derivative of codeine in which the 6-hydroxy group has been replaced by chlorine. See also
References1. ^{{Cite journal |title=The SN2' Reaction. III. Structure and SN2' Reactions of the Halocodides| author = Stork, Gilbert | authorlink = Gilbert Stork | journal = Journal of the American Chemical Society | year = 1956 | volume = 78 | pages = 4619–4624 | doi = 10.1021/ja01599a026 | last2 = Clarke | first2 = Frank H. | issue = 18}} {{Opioidergics}}{{DEFAULTSORT:Chlorocodide, alpha-}}{{analgesic-stub}} 2 : Opioids|Organochlorides |
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