| 词条 | Alphafusellovirus | |||||||||||||||||||||||||||
| 释义 |
| virus_group = i | familia = Fuselloviridae | genus = Alphafusellovirus | subdivision_ranks = Type Species | subdivision =
}}Alphafusellovirus is a genus of viruses, in the family Fuselloviridae. Species in the genus Sulfolobus (sulfolobus shibatae, Sulfolobus solfataricus, and Sulfolobus islandicus) serve as natural hosts. There are currently seven species in this genus including the type species Sulfolobus spindle-shaped virus 1 (SSV1 or SSV-1)[1][2] TaxonomyGroup: dsDNA{{Collapsible list|title= Order: Unassigned|1={{Collapsible list| framestyle=border:none; padding:1.0em;|title=Family: Fuselloviridae |1={{hidden begin|title=Genus: Alphafusellovirus}}
SSV may also stand for 'Simian sarcoma virus' which is a synonym of 'Woolly monkey sarcoma virus (WMSV)' (fam. Retroviridae). SSV6 belongs to the genus Betafusellovirus. {{hidden end}}}} }}[2] StructureViruses in Alphafusellovirus are enveloped, with lemon-shaped geometries. The diameter is around 60 nm, with a length of 100 nm. Genomes are circular, around 17.3kb in length.[1] Biochemical characterization of SSV1, the type species of the Alphafusellovirus genus, showed that virions are composed of four virus-encoded structural proteins, VP1 to VP4, as well as one DNA-binding chromatin protein of cellular origin. The virion proteins VP1, VP3, and VP4 undergo posttranslational modification by glycosylation, seemingly at multiple sites. VP1 is also proteolytically processed. SSV1 virions contain glycerol dibiphytanyl glycerol tetraether (GDGT) lipids, which appear to be acquired by the virus in a selective manner from the host cytoplasmic membrane.[3]
Life cycleViral replication is cytoplasmic. Entry into the host cell is achieved by adsorption into the host cell. Dna templated transcription is the method of transcription. Sulfolobus shibatae, sulfolobus solfataricus, and sulfolobus islandicus serve as the natural host.[1] It has been demonstrated that SSV1, the type species of the genus, is released from the host without causing cell lysis by a budding mechanism, similar to that employed by enveloped eukaryotic viruses.[4]
References1. ^1 2 {{cite web|title=Viral Zone|url=http://viralzone.expasy.org/all_by_species/534.html|publisher=ExPASy|accessdate=12 June 2015}} 2. ^1 {{cite web|last1=ICTV|title=Virus Taxonomy: 2014 Release|url=http://ictvonline.org/virusTaxonomy.asp|accessdate=12 June 2015}} 3. ^{{cite journal|vauthors=Quemin ER, Pietilä MK, Oksanen HM, Forterre P, Rijpstra WI, Schouten S, Bamford DH, Prangishvili D, Krupovic M |title=Sulfolobus spindle-shaped virus 1 contains glycosylated capsid proteins, a cellular chromatin protein, and host-derived lipids|journal=J Virol|date=2015|volume=89|issue=22|pages=11681–11691|doi=10.1128/JVI.02270-15|pmid=26355093|pmc=4645638}} 4. ^{{cite journal|vauthors=Quemin ER, Chlanda P, Sachse M, Forterre P, Prangishvili D, Krupovic M |title=Eukaryotic-Like Virus Budding in Archaea|journal=mBio|date=2016|volume=7|issue=5|page=e01439-16|doi=10.1128/mBio.01439-16|pmid=27624130|pmc=5021807}} External links
2 : Bacteriophages|Fuselloviridae |
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