词条 | AM-2232 |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451605653 | IUPAC_name = 5-(3-(1-naphthoyl)-1H-indol-1-yl)pentanenitrile | image = AM-2232_structure.png | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = Schedule II | legal_DE = Anlage II | legal_UK = | legal_US = | legal_NZ = Temporary Class | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 335161-19-8 | ATC_prefix = | ATC_suffix = | PubChem = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 26633898 | smiles = c1ccc2c(c1)cccc2C(=O)c3cn(c4c3cccc4)CCCCC#N | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C24H20N2O/c25-15-6-1-7-16-26-17-22(20-12-4-5-14-23(20)26)24(27)21-13-8-10-18-9-2-3-11-19(18)21/h2-5,8-14,17H,1,6-7,16H2 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = VWVAIBKHFCUSMD-UHFFFAOYSA-N | C=24 | H=20 | N=2 | O=1 | molecular_weight = 352.428 g/mol }}AM-2232 (1-(4-cyanobutyl)-3-(naphthalen-1-oyl)indole) is a drug that acts as a potent but unselective agonist for the cannabinoid receptors, with a Ki of 0.28 nM at CB1 and 1.48 nM at CB2.[1] See also
References1. ^{{Ref patent2 | country = US | number = 7241799 | status = granted | title = Cannabimimetic indole derivatives | pubdate = 2004-11-05 | gdate = 2007-07-10 | pridate= 2004-11-05 | inventor = Makriyannis A, Deng H | assign1= }} {{Cannabinoids}}{{cannabinoid-stub}} 5 : Cannabinoids|Naphthoylindoles|Nitriles|AM cannabinoids|Designer drugs |
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