词条 | Andreas Engel |
释义 |
See Andreas Angelus for the 16th-century chronicler.{{Infobox scientist |name = Andreas Engel |image = Andreas Engel 2009.jpg |image_size = |caption = Andreas Engel (2009) |birth_date = |birth_place = |death_date = |death_place = |residence = |citizenship = |nationality = Swiss |ethnicity = |field = Structural biology |work_institutions = Johns Hopkins University, Biozentrum University of Basel |alma_mater = |doctoral_advisor = |doctoral_students = |known_for = |author_abbrev_bot = |author_abbrev_zoo = |influences = |influenced = |prizes = |religion = |footnotes = |signature = }} Andreas Engel is a Swiss structural biologist and co-founder of the Maurice E. Müller Institute for Structural Biology at the Biozentrum of the University of Basel. LifeEngel studied physics and mathematics in Bern (PhD 1972) and at the Johns Hopkins University, Baltimore. In 1974 he joined the Biozentrum Basel. In 1986, after work in industry, he became Professor for Structural Biology. Engel and Ueli Aebi established the Maurice E. Müller Institute for Structural Biology.[1] After becoming professor emeritus in 2010,[2] Engel joined the Case Western Reserve University, to build up the Cleveland Center for Membrane and Structural Biology.[3] He worked at the Department of Bionanoscience,[4] part of the Kavli Institute of Nanoscience and TU Delft until his retirement in 2018. Engel loves to ski, climb, and sketch. Work{{BLP sources section|date=October 2014}}Engel pioneered the application of scanning transmission electron microscopy (STEM) and atomic force microscopy (AFM) to image biomolecular complexes. Mass measurements using STEM, 2-dimensional crystallization of membrane proteins, cryo-electron crystallography and AFM were applied to study the structure of supramolecular assemblies [5]. Gram negative and positive pathogens, as well as bacterial envelopes were analyzed. Fujiyoshi and Engel solved the structure of Aquaporin-1 in collaboration with Agre.[5] Together with Palczewski Engel’s team discovered the packing arrangement of rhodopsin in the retina.[6] Engel developed the first curriculum in nanoscale sciences that attracted many young talents to the University of Basel. Similar programs have since been implemented in many top universities. Awards and honors
References1. ^{{cite journal |author=Müller SA, Engel A |title=Looking back at a quarter-century of research at the Maurice E. Müller Institute for Structural Biology |journal=J. Struct. Biol. |volume=177 |issue=1 |pages=3–13 |date=January 2012 |pmid=22115996 |doi=10.1016/j.jsb.2011.11.013}} 2. ^{{cite web |url=http://www.biozentrum.unibas.ch/news-events/news/news-details/article/farewell-symposium-for-andreas-engel/ |title=Farewell Symposium for Andreas Engel |publisher=unibas.ch |date= |accessdate=2015-10-15}} 3. ^{{cite web|url=http://pharmacology.case.edu/department/faculty/primary/Pages%5Cengel.aspx |title=Case Western Reserve University, Department of Pharmacology |publisher=case.edu |date= |accessdate=2014-02-04 |deadurl=yes |archiveurl=https://web.archive.org/web/20140228180917/http://pharmacology.case.edu/department/faculty/primary/Pages/engel.aspx |archivedate=2014-02-28 }} 4. ^{{cite web|url=http://www.tnw.tudelft.nl/en/about-faculty/departments/bionanoscience/people/scientific-staff/prof-andreas-engel/ |title=TU Delft, People Bionanoscience Department |publisher=tudelft.nl |date= |accessdate=2014-02-04 |deadurl=yes |archiveurl=https://web.archive.org/web/20140223123830/http://www.tnw.tudelft.nl/en/about-faculty/departments/bionanoscience/people/scientific-staff/prof-andreas-engel/ |archivedate=2014-02-23 }} 5. ^{{cite journal |title=Aquaporin water channels – from atomic structure to clinical medicine | doi=10.1113/jphysiol.2002.020818 | pmid=12096044 |volume=542 |issue=1 |journal=The Journal of Physiology |pages=3–16|pmc=2290382 |year = 2002|last1 = Agre|first1 = P.| last2=King | first2=L. S. | last3=Yasui | first3=M. | last4=Guggino | first4=W. B. | last5=Ottersen | first5=O. P. | last6=Fujiyoshi | first6=Y. | last7=Engel | first7=A. | last8=Nielsen | first8=S. }} 6. ^{{cite web|url=http://pharmacology.cwru.edu/department/faculty/primary/pages/Palczewski/articles/sdarticle.pdf |title=Structure of the rhodopsin dimer: a working model for G-protein-coupled receptors |publisher=cwru.edu |accessdate=2014-02-04 |deadurl=yes |archiveurl=https://web.archive.org/web/20140221162109/http://pharmacology.cwru.edu/department/faculty/primary/pages/Palczewski/articles/sdarticle.pdf |archivedate=2014-02-21 }} 7. ^{{cite web|url=http://www.au.dk/en/annualcelebration/tidligere-aarsfester/aarhusuniversitysannualcelebration/honorary-doctor-andreas-engel/ |title=Honorary Doctor Andreas Engel |publisher=au.dk |date= |accessdate=2014-02-04 |deadurl=yes |archiveurl=https://web.archive.org/web/20140304192444/http://www.au.dk/en/annualcelebration/tidligere-aarsfester/aarhusuniversitysannualcelebration/honorary-doctor-andreas-engel/ |archivedate=2014-03-04 }} External links
7 : Living people|Johns Hopkins University alumni|Members of the European Molecular Biology Organization|University of Basel alumni|Biozentrum University of Basel|Swiss biologists|Year of birth missing (living people) |
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