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词条 Angiomatoid fibrous histiocytoma
释义

  1. Pathology

  2. Diagnosis

  3. Treatment

  4. See also

  5. References

  6. External links

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Angiomatoid fibrous histiocytoma, abbreviated AFH, is a rarely metastasizing tumour that affects children and young adults.

Pathology

It is characterized cystic blood-filled spaces and composed of histiocyte-like cells. A lymphocytic cuff is common. It often simulates a vascular lesion, and was initially described as doing this.[1]

AFH typically has a chromosomal translocation involving the ATF1 gene -- t(12;16) FUS/ATF1 or t(12;22) EWS/ATF1.

Diagnosis

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Treatment

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See also

  • Granulomatous inflammation
  • Vascular tumour

References

1. ^{{Cite journal | last1 = Enzinger | first1 = FM. | title = Angiomatoid malignant fibrous histiocytoma: a distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm. | journal = Cancer | volume = 44 | issue = 6 | pages = 2147–57 |date=Dec 1979 | doi = 10.1002/1097-0142(197912)44:6<2147::aid-cncr2820440627>3.0.co;2-8| PMID = 228836 }}

External links

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1 : Soft tissue disorders

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