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词条 Angiomyofibroblastoma
释义

  1. Location

  2. Pathology

      Immunohistochemistry  

  3. References

{{technical|date=May 2014}}

Angiomyofibroblastoma is an uncommon benign mesenchymal tumor. It occurs almost in the vulvovaginal area of women, but can also be observed in men.

The gross features of AMFB are well-circumscribed. Usually, most tumors grow slowly, and patients do not feel pain. It also has low tendency for local recurrence.

Location

  • In women
    • Female genital tract[1]
    • Vulva[2]
    • Posterior perivesical space[3]
  • In men
    • Spermatic cord[4]

Pathology

Microscopical examination shows abundant thin-walled blood vessels with hypocellular and hypercellular areas.

Immunohistochemistry

Almost all tumor cells have immunoreactivity for both desmin and vimentin. It also express estrogen receptors and/or progesterone receptors, but staining for cytokeratin is negative.[5]

References

1. ^{{Cite journal | pmid = 11776120| year = 2000| author1 = Wang| first1 = J| title = Clinicopathologic analysis of angiomyofibroblastoma of the female genital tract| journal = Chinese Medical Journal| volume = 113| issue = 11| pages = 1036–9| last2 = Sheng| first2 = W| last3 = Tu| first3 = X| last4 = Shi| first4 = D| last5 = Zhu| first5 = X| last6 = Zhang| first6 = R}}
2. ^{{Cite journal | pmid = 24328028| year = 2013| author1 = Seo| first1 = J. W.| title = Angiomyofibroblastoma of the vulva| journal = Obstetrics & Gynecology Science| volume = 56| issue = 5| pages = 349–51| last2 = Lee| first2 = K. A.| last3 = Yoon| first3 = N. R.| last4 = Lee| first4 = J. W.| last5 = Kim| first5 = B. G.| last6 = Bae| first6 = D. S.| doi = 10.5468/ogs.2013.56.5.349| pmc = 3784123}}
3. ^{{Cite journal | pmid = 18682679| year = 2008| author1 = Lim| first1 = K. J.| title = Angiomyofibroblastoma arising from the posterior perivesical space: A case report with MR findings| journal = Korean Journal of Radiology| volume = 9| issue = 4| pages = 382–5| last2 = Moon| first2 = J. H.| last3 = Yoon| first3 = D. Y.| last4 = Cha| first4 = J. H.| last5 = Lee| first5 = I. J.| last6 = Min| first6 = S. J.| doi = 10.3348/kjr.2008.9.4.382| pmc = 2627271}}
4. ^{{Cite journal | pmid = 20202207| year = 2010| author1 = Tzanakis| first1 = N. E.| title = Angiomyofibroblastoma of the spermatic cord: A case report| journal = Journal of Medical Case Reports| volume = 4| pages = 79| last2 = Giannopoulos| first2 = G. A.| last3 = Efstathiou| first3 = S. P.| last4 = Rallis| first4 = G. E.| last5 = Nikiteas| first5 = N. I.| doi = 10.1186/1752-1947-4-79| pmc = 2838917}}
5. ^{{Cite journal | pmid = 24328028| year = 2013| author1 = Seo| first1 = J. W.| title = Angiomyofibroblastoma of the vulva| journal = Obstetrics & Gynecology Science| volume = 56| issue = 5| pages = 349–51| last2 = Lee| first2 = K. A.| last3 = Yoon| first3 = N. R.| last4 = Lee| first4 = J. W.| last5 = Kim| first5 = B. G.| last6 = Bae| first6 = D. S.| doi = 10.5468/ogs.2013.56.5.349| pmc = 3784123}}
{{Neoplasm-stub}}

1 : Soft tissue tumor

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