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词条 Anode break excitation
释义

  1. Further reading

  2. External links

  3. See also

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Anode break excitation (ABE) is an electrophysiological phenomenon whereby a neuron fires action potentials in response to termination of a hyperpolarizing current.

When a hyperpolarizing current is applied across a membrane, the electrical potential across the membrane falls (becomes negative of the resting potential); this fall is followed by a drop in the threshold required for action potential (since the threshold is directly linked to the potential across the membrane - they rise and fall together).

ABE arises after the hyperpolarizing current is terminated: the potential across the cell rises rapidly with the absence of hyperpolarizing stimulus, but the action potential threshold stays at its lowered value. As a result, the potential is suprathreshold: sufficient to cause an action potential within the cell.

Further reading

  • {{cite journal | vauthors = Hodgkin AL, Huxley AF | title = A quantitative description of membrane current and its application to conduction and excitation in nerve | journal = The Journal of Physiology | volume = 117 | issue = 4 | pages = 500–44 | date = August 1952 | pmid = 12991237 | pmc = 1392413 | doi = 10.1113/jphysiol.1952.sp004764 }}

External links

  • [https://hobbieroth.blogspot.com/2017/09/anode-break-excitation.html A description of anode break excitation.]

See also

  • Action potential
  • Hodgkin–Huxley model
  • Neural accommodation

1 : Electrophysiology

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