Arbuckle is a surname. Notable people with the surname include:

• Andrew Arbuckle (born 1944), Scottish Liberal Democrat politician
• Andrew Arbuckle (actor) (1887–1938), American actor, brother of Macklyn and cousin of Roscoe
• Charles Arbuckle (born 1968), American football player
• David Arbuckle (born 1973), Scottish footballer
• Ernest C. Arbuckle (1912–1986), American business leader
• Gary Arbuckle (born 1984), Scottish football player
• James Arbuckle (1700 – c. 1742), Irish poet
• John Arbuckle (politician), see 15th General Assembly of Prince Edward Island
• John Arbuckle, see Black Coffee (2005 film)
• John Arbuckle of John Arbuckle v. Joseph E Blackburn, see List of United States Supreme Court cases, volume 191
• Jon Arbuckle, fictional owner of Garfield the cat
• Macklyn Arbuckle (1866–1931), American actor, brother of Andrew and cousin of Roscoe
• Matthew Arbuckle Sr. (1740-1781), American military officer of the 18th Century
• Matthew Arbuckle Jr. (1778–1851), American military officer of the 19th Century
• Phillip Arbuckle (1883–1932), American football coach
• Roscoe "Fatty" Arbuckle (1887–1933), American silent film comedian
• Samuel Arbuckle (1804–1874), Californian politician
• Steve Arbuckle, Canadian actor
• Tiffany Arbuckle, the name of Christian singer Plumb
• Randall Arbuckle (born 1990), American Football Player

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