| 词条 | Oxyphil cell (parathyroid) |
| 释义 |
| Name = Oxyphil cell | Latin = | Greek = | Image = Parathyroid gland high mag-cropped2.jpg | Caption = High magnification micrograph of parathyroid. H&E stain. The cells with orange/pink staining cytoplasm are oxyphil cells | Width = | Image2 = | Caption2 = | Precursor = | System = | Location = Parathyroid gland }} In the parathyroid gland, the parathyroid oxyphil cell is larger and lighter staining than the parathyroid chief cell.[1] These cells can be found in clusters in the center of the section and at the periphery.[2][3][4][5] Oxyphil cells appear at the onset of puberty, but have no known function. With nuclear medicine scans, they selectively take up the Technetium-sestamibi complex radiotracer to allow delineation of glandular anatomy.[6] Oxyphil cells have been shown to express parathyroid-relevant genes found in the chief cells and have the potential to produce additional autocrine/paracrine factors, such as parathyroid hormone-related protein (PTHrP) and calcitriol.[7] More work needs to be done to fully understand the functions of these cells and their secretions. See also
References1. ^{{BUHistology|15002loa|inline=1}} {{Endocrine system anatomy}}{{Authority control}}{{Cell-biology-stub}}2. ^Gartner, p. 208, Fig. 3 3. ^Ross, p. 628, Fig. 1 4. ^DiFiore, pp. 270 - 271 5. ^Wheater, pp. 312 - 313 6. ^"Minimally Invasive Radio-guided Surgery for Primary Hyperparathyroidism," Annals of Surgical Oncology 12/07 14(12) pp 3401-3402 7. ^{{cite journal|last=Ritter, Haughey, Miller, Brown|journal=J Clin Endocrinol Metab|year=2012|pmid=22585091|doi=10.1210/jc.2011-3366|volume=97|issue=8|title=Differential gene expression by oxyphil and chief cells of human parathyroid glands|pages=E1499–505|pmc=3591682}} 3 : Endocrine cells|Human cells|Parathyroid |
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