词条 | Argadin |
释义 |
| Watchedfields = changed | verifiedrevid = 477350518 | ImageFile = Argadrin.png | ImageSize = 300px | ImageAlt = | IUPACName = | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|??}} | CASNo = 289665-92-5 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB04350 | PubChem = 449123 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 445236 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 395740 | SMILES = O=C1N2[C@H](O)C[C@@H]1NC(=O)[C@@H]4N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2Cc3c[nH]cn3)CCCC(=O)O)CCC/N=C(\)NC(=O)C)CCC4 | InChI = 1/C29H42N10O9/c1-15(40)34-29(30)32-9-3-6-18-27(47)38-10-4-7-20(38)25(45)37-19-12-22(41)39(28(19)48)21(11-16-13-31-14-33-16)26(46)35-17(24(44)36-18)5-2-8-23(42)43/h13-14,17-22,41H,2-12H2,1H3,(H,31,33)(H,35,46)(H,36,44)(H,37,45)(H,42,43)(H3,30,32,34,40)/t17-,18-,19-,20+,21-,22+/m0/s1 | InChIKey = FOZYKTUSOWWQGR-KNPYFFGGBM | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C29H42N10O9/c1-15(40)34-29(30)32-9-3-6-18-27(47)38-10-4-7-20(38)25(45)37-19-12-22(41)39(28(19)48)21(11-16-13-31-14-33-16)26(46)35-17(24(44)36-18)5-2-8-23(42)43/h13-14,17-22,41H,2-12H2,1H3,(H,31,33)(H,35,46)(H,36,44)(H,37,45)(H,42,43)(H3,30,32,34,40)/t17-,18-,19-,20+,21-,22+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = FOZYKTUSOWWQGR-KNPYFFGGSA-N |Section2={{Chembox Properties | Formula = | C=29 | H=42 | N=10 | O=9 | MolarMass = 674.7 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Argadin is a cyclic peptide natural product, investigated for its ability to be a nanomolar inhibitor of Family-18 Chitinases.[1] References1. ^{{Cite journal| DOI = 10.1002/ejoc.200600599| volume = 22| issue = | pages = 5002–5006| last = Dixon| first = Mark|author2=Ole A. Andersen |author3=Daan M. F. van Aalten |author4=Ian M. Eggleston| title = First Synthesis of Argadin: A Nanomolar Inhibitor of Family-18 Chitinases| journal = Journal of Drugs in Dermatology: JDD| year=2006}} 1 : Cyclic peptides |
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