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词条 Artemisinic aldehyde Delta11(13)-reductase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Artemisinic aldehyde Delta11(13)-reductase
| EC_number = 1.3.1.92
| CAS_number =
| IUBMB_EC_number = 1/3/1/92
| GO_code =
| image =
| width =
| caption =
}}Artemisinic aldehyde Delta11(13)-reductase ({{EC number|1.3.1.92}}, Dbr2) is an enzyme with systematic name artemisinic aldehyde:NADP+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction

(11R)-dihydroartemisinic aldehyde + NADP+ artemisinic aldehyde + NADPH + H+

This enzyme i present in Artemisia annua.

References

1. ^{{cite journal | title = Identification of intermediates and enzymes involved in the early steps of artemisinin biosynthesis in Artemisia annua |author1 = Bertea, C.M. |author2 =Freije, J.R. |author3 =van der Woude, H. |author4 =Verstappen, F.W. |author5 =Perk, L. |author6 =Marquez, V. |author7 =De Kraker, J.W. |author8 =Posthumus, M.A. |author9 =Jansen, B.J. |author10 =de Groot, A. |author11 =Franssen, M.C. |author12 =Bouwmeester, H.J. | journal = Planta Med. |year = 2005 |volume = 71 |pages = 40–47 |pmid = 15678372 |doi=10.1055/s-2005-837749 |issue=1}}
2. ^{{cite journal | title = The molecular cloning of artemisinic aldehyde Δ11(13) reductase and its role in glandular trichome-dependent biosynthesis of artemisinin in Artemisia annua |author1 = Zhang, Y. |author2 =Teoh, K.H. |author3 =Reed, D.W. |author4 =Maes, L. |author5 =Goossens, A. |author6 =Olson, D.J. |author7 =Ross, A.R. |author8 =Covello, P.S. | journal = J. Biol. Chem. |year = 2008 |volume = 283 |pages = 21501–21508 |pmid = 18495659 |doi=10.1074/jbc.M803090200 |issue=31}}

External links

  • {{MeshName|Artemisinic+aldehyde+Delta11(13)-reductase}}
{{CH-CH oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.3.1

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