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Artyukhin ({{lang-ru|Артюхин}}) is a Russian masculine surname, its feminine counterpart is Artyukhina. It may refer to - Alexandra Artyukhina (1889–1969), Russian revolutionary
- Evgeny Artyukhin (born 1983), Russian hockey player
- Evgeny Artyukhin, Sr. (1949–2008), Soviet Greco-Roman wrestler
- Sergei Artyukhin (1976–2012), Russian-Belarusian Greco-Roman wrestler, brother of Evgeny and son of Evgeny Sr.
- Yury Artyukhin, (1930–1998) Russian cosmonaut
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