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词条 Ary L. Goldberger
释义

  1. References

Ary Louis Goldberger (b. Bronx, New York City, May 29, 1949) is a physician-educator, whose collaborative research work is at the interface of biomedicine and complexity science (nonlinear dynamics).[1][2] He holds a BA from Harvard College and an MD from Yale Medical School. He did his clinical training in internal medicine and cardiovascular disease at Yale–New Haven Hospital and at the University of California, San Diego, respectively. He currently serves as Professor of Medicine at Harvard Medical School[3] and was one of the Core Founding Faculty (2010-2015) of the Wyss Institute for Biologically Inspired Engineering at Harvard University.[4]

Goldberger is founding and current Principal Investigator (with R. G. Mark at MIT) of the NIH-sponsored Research Resource for Complex Physiologic Signals.[5] The “Big Data” PhysioNet Resource is the first and remains the largest repository of free, open-access databases and open-source computational tools devoted to complex signals informatics. In addition, he is founding and current Director of the Margret and H.A. Rey Institute for Nonlinear Dynamics in Physiology and Medicine at Beth Israel Deaconess Medical Center (BIDMC) in Boston.[6][7]

Goldberger is the senior author of two textbooks on clinical electrocardiography.[8][9][10] He and his colleagues at BIDMC are developers of ECG Wave-Maven,[11] the largest and most–widely used free teaching site for ECG self-assessment. He is also co-author of a recent book on critical thinking for students of medicine and their mentors.[12]

His scientific investigations focus on nonlinear mechanisms of healthy function and their alterations with pathology. He and his colleagues were the first to identify the fractal dynamics of the healthy heartbeat and describe alterations in fractal scaling with life-threatening conditions such as heart failure.[13][14][15] Goldberger and colleagues originated and continue to elaborate the complexity-loss theory of aging and disease[16][17][18][19][20][21] which is widely cited in basic science and clinical research.

Some of this work was featured on the 2011 PBS-NOVA show: Hunting the Hidden Dimension. Among other honors, he is a recipient of the S. Robert Stone Award for Excellence in Teaching at Harvard Medical School/BIDMC and an Ellison Medical Foundation Senior Scholar in Aging Award.

Goldberger and colleagues, R.G Mark and G.B. Moody, are recipients of the 2016 Laufman-Greatbatch Award from the Association for the Advancement of Medical Instrumentation (AAMI). This honor, the highest conferred by the AAMI Foundation, recognizes work over the last 20 years to collect and provide open access to “big data” and software tools through the creation of the PhysioNet Resource.[22]

References

1. ^{{Citation |vauthors=Goldberger AL, Rigney DR, West BJ | title = Chaos and fractals in human physiology | journal = Sci Am |year = 1990 | volume = 262 |issue=2 |pages = 42–9 |url =http://reylab.bidmc.harvard.edu/pubs/1990/sa-1990-262-42.pdf | doi=10.1038/scientificamerican0290-42| pmid = 2296715 }}
2. ^{{Citation |author= Goldberger AL. |title = Giles F. Filley Lecture. Complex Systems. |journal= Proc Am Thor Soc |year=2006 |volume=3 |issue=6|pages=467–71|doi=10.1513/pats.200603-028MS |pmid=16921107 |pmc=2647633}}
3. ^{{cite web |title = Ary Louis Goldberger, M.D. |url = http://connects.catalyst.harvard.edu/Profiles/display/Person/3288 | publisher = Harvard Catalyst Profiles | accessdate = March 2014}}
4. ^{{cite web|title=Ary Goldberger, M.D. |url=http://wyss.harvard.edu/viewpage/122/ary-goldberger |archive-url=https://web.archive.org/web/20091010021024/http://wyss.harvard.edu/viewpage/122/ary-goldberger |dead-url=yes |archive-date=2009-10-10 |publisher=Wyss Institute |accessdate=March 2014 }}
5. ^PhysioNet
6. ^ReyLab
7. ^{{cite web |title = Ary Goldberger, M.D. |url = http://reylab.bidmc.harvard.edu/people/Ary.shtml | publisher = Margret and H.A. Rey Institute | accessdate = March 2014}}
8. ^{{cite journal|last=Henning|first=Robert J.|year=1976|title=Myocardial Infarction: Electrocardiographic Differential Diagnosis|journal=JAMA: The Journal of the American Medical Association|volume=235|issue=26|page=2865|issn=0098-7484|doi=10.1001/jama.1976.03260520057033}}
9. ^{{cite book|author= Goldberger AL | title = Myocardial Infarction: Electrocardiographic Differential Diagnosis . | edition = 4th | location = St. Louis | publisher = Mosby-Year Book| year = 1991|isbn = 9780801618567 }}
10. ^{{cite book|vauthors=Goldberger AL, Goldberger ZD, Shvilkin A | title = Goldberger's Clinical Electrocardiography: A Simplified Approach . | edition = 8th | location = Philadelphia | publisher = Elsevier | year = 2012|isbn = 9780323087865 }}
11. ^ECG Wave-Maven
12. ^{{cite journal|last=McMahon|first=Eimear|author2=Brian Hallahan |date=May 2013|title=Review of 'Becoming a consummate clinician – what every student, house officer and hospital practitioner needs to know' (review)|journal=Irish Journal of Psychological Medicine|volume=30|issue=2|doi=10.1017/ipm.2013.11|pages=160–161}}
13. ^{{ Citation |vauthors=Goldberger AL, Bhargava V, West BJ, Mandell AJ |title= On a mechanism of cardiac electrical stability. The fractal hypothesis. |year=1985|volume=48|issue=3|pages=525–8|doi=10.1016/s0006-3495(85)83808-x|issn=0006-3495|pmid=4041542 |journal=Biophys J |pmc=1329366}}
14. ^{{ Citation |vauthors=Goldberger AL, West BJ |title = Fractals in physiology and medicine |journal=Yale J Biol Med |year=1987|volume=60|issue = 5 |pages=421–35|issn= 0044-0086|pmid=3424875 |pmc=2590346}}
15. ^{{ Citation |author1=Goldberger AL |author2=Amaral LAN |author3=Hausdorff JM |author4=Ivanov PCh |author5=Peng CK |author6=Stanley HE. |title= Fractal dynamics in physiology: alterations with disease and aging. |journal=Proc Natl Acad Sci USA |year=2002|volume=99 |issue = Suppl 1 |pages=2466–2472|issn= 0027-8424|doi= 10.1073/pnas.012579499|pmid=11875196 |pmc=128562}}
16. ^{{Citation |vauthors=Goldberger AL, Findley L, Blackburn MJ, Mandell AJ |title= Nonlinear dynamics of heart failure: implications of long-wavelength cardiopulmonary oscillations. |year=1984 |volume=107|issue=3|pages=612–5|issn= 0002-8703|pmid=6695715 |journal=Am Heart J |doi=10.1016/0002-8703(84)90120-0}}
17. ^{{ Citation |author=Goldberger AL. |title= Fractals and the birth of Gothic: reflections on the biologic basis of creativity |journal=Molecular Psychiatry |year=1996|volume=1|issue= 2 |pages=99–104|issn= 1359-4184|pmid=9118332}}
18. ^{{ Citation |vauthors=Lipsitz LA, Goldberger AL |title= Loss of "complexity" and aging. Potential applications of fractals and chaos theory to senescence. |journal= JAMA |year=1992|volume=267|issue=13|pages=1806–09|issn= 0098-7484 |pmid=1482430 |doi=10.1001/jama.1992.03480130122036}}
19. ^{{ Citation |vauthors=Costa M, Goldberger AL, Peng CK |title= Multiscale entropy analysis of complex physiologic time series |year=2002|volume=89|issue= 6 |pages=068102–1–4|issn=0031-9007|pmid=12190613 |doi=10.1103/physrevlett.89.068102 |journal=Phys Rev Lett|citeseerx=10.1.1.377.7077}}
20. ^{{ Citation |vauthors=Cancio LC, Batchinsky AI, Baker WL, Necsoiu C, Salinas J, Goldberger AL, Costa MD |title= Combat casualties undergoing lifesaving interventions have decreased heart rate complexity at multiple time scales. |journal= J Crit Care |year=2013|volume=28|issue=6|pages=1093–8|doi= 10.1016/j.jcrc.2013.08.022|issn= 1557-8615|pmid=24140167 |pmc=4018756}}
21. ^{{ Citation |vauthors=Costa MD, Schnettler WT, Amorim-Costa C, Bernardes J, Costa A, Goldberger AL, Ayres-de-Campos D |title=Complexity-loss in fetal heart rate dynamics during labor as a potential biomarker of acidemia. |journal=Early Hum Dev |year=2014|volume=90|issue=1|pages=67–71|doi= 10.1016/j.earlhumdev.2013.10.002|issn= 1872-6232 |pmid=24290526 |pmc=4077599}}
22. ^AAMI Foundation's Laufman-Greatbatch Award
{{DEFAULTSORT:Goldberger, Ary L.}}

7 : Year of birth missing (living people)|Living people|American cardiologists|American systems scientists|Biogerontologists|Harvard College alumni|Yale School of Medicine alumni
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