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词条 Autoimmune oophoritis
释义

  1. Signs and symptoms

  2. Causes

  3. Diagnoses

  4. References

  5. External links

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Autoimmune oophoritis is a rare autoimmune disease where the body's immune system mistakenly attacks the ovaries.[1] This causes the ovaries to have inflammation, atrophy and fibrosis. The changes to the ovaries can cause them to not function properly.

Signs and symptoms

  • Primary amenorrhea – where menstruation has never occurred
  • Secondary amenorrhea – where menstruation occurred once puberty happened but then later stopped
  • Infertility
  • Sex hormone deficiency
  • Lower abdominal pain
  • Fever
  • Malaise
  • Vaginal discharge
  • Irregular bleeding or absent menstrual period – also known as amenorrhea
  • Symptoms that are related to cysts

Causes

The underlying cause of autoimmune oophoritis is unknown. In many cases it can be a part of lupus, pernicious anemia, myasthenia gravis, or other autoimmune conditions. Autoimmune oophoritis can be associated with autoimmune polyglandular syndrome type I and type II.[2]

Diagnoses

Diagnosis involves a special blood test which looks for anti-steroid or anti-ovarian antibodies, a pelvic ultrasound to look for enlarged cystic ovaries, and other type of tests to rule out other issues that can be a part of primary ovarian insufficiency (POI).[2]

References

1. ^{{cite book|last1=Mackay|first1=edited by Noel R. Rose, Ian R.|title=The autoimmune diseases|date=2006|publisher=Elsevier Academic Press|location=St. Louis, MO|isbn=978-0-12-595961-2|edition=4th|ref=Chapter 68}}
2. ^{{Cite web|url=https://rarediseases.info.nih.gov/diseases/9461/autoimmune-oophoritis|title=Autoimmune oophoritis|last=|first=|date=|website=NIH.gov|language=en|archive-url=|archive-date=|dead-url=|access-date=2018-08-07}}
{{Include-USGov
|agency=National Institutes of Health
|policy=https://rarediseases.info.nih.gov/diseases/9461/autoimmune-oophoritis}}

External links

{{Medical resources
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2 : Inflammatory diseases of female pelvic organs|Autoimmune diseases

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