词条 | Bennet Omalu |
释义 |
|name = Dr. Bennet Omalu |honorific_suffix = |image = Omalu_Picture_(7).jpg |alt = |caption = Bennet Omalu in 2015 |birth_date = {{birth date and age|1968|9|30}}[1] |birth_place = Nnokwa, Idemili South, Anambra State, Nigeria |death_date = |death_place = |residence = Lodi, California |nationality = Nigerian and naturalized US citizen |other_names = |alma_mater = University of Nigeria, Nsukka (MBBS, 1990) University of Pittsburgh Graduate School of Public Health (MPH, Epidemiology, 2004) Carnegie Mellon University (MBA, 2008) |occupation = Medical Doctor, Forensic Pathologist, Professor, Medical Examiner |years_active = |known_for = The first to discover and publish findings of chronic traumatic encephalopathy in American football players while working at the Allegheny County Coroner's Office in Pittsburgh.[2] |notable_works = Truth Doesn't Have a Side: My Alarming Discovery about the Danger of Contact Sports |spouse = Prema Mutiso |children = 2 |birth_names = |website = {{URL|www.bennetomalu.com/}} }} Bennet Ifeakandu Omalu (born September 1968[1]) is a Nigerian-American physician, forensic pathologist, and neuropathologist who was the first to discover and publish findings of chronic traumatic encephalopathy (CTE) in American football players while working at the Allegheny County Coroner's Office in Pittsburgh.[2] He later became the chief medical examiner for San Joaquin County, California, and is a professor at the University of California, Davis, Department of Medical Pathology and Laboratory Medicine. Early lifeOmalu was born in Nnokwa, Idemili South, Anambra in southeastern Nigeria on September 30, 1968, the sixth of seven siblings. He was born during the Nigerian Civil War, which caused his family to flee from their home in the predominantly Igbo village of Enugu-Ukwu in southeastern Nigeria. They returned two years after Omalu's birth.[3] Omalu's mother was a seamstress and his father a civil mining engineer and community leader in Enugu-Ukwu. The family name, Omalu, is a shortened form of the surname, Onyemalukwube, which translates to "he who knows, speak."[3] Education and careerOmalu began primary school at age three and earned entrance into the Federal Government College Enugu for secondary school. He attended medical school starting at age 16 at the University of Nigeria, Nsukka. After graduating with a Bachelor of Medicine and Bachelor of Surgery (MBBS) in June 1990, he completed a clinical internship, followed by three years of service work doctoring in the highland city of Jos. He became disillusioned with Nigeria after presidential candidate Moshood Abiola failed to win the Nigerian presidency during an inconclusive election in 1993[3] and began to search for scholarship opportunities in the United States. Omalu first came to Seattle, Washington in 1994 to complete an epidemiology fellowship at the University of Washington. In 1995, he left Seattle for New York City, where he joined Columbia University's Harlem Hospital Center for a residency training program in anatomic and clinical pathology. Before residency, he trained as a forensic pathologist under noted forensic consultant Cyril Wecht at the Allegheny County Coroner's Office in Pittsburgh. Omalu became particularly interested in neuropathology. Omalu holds eight advanced degrees and board certifications, later receiving fellowships in pathology and neuropathology through the University of Pittsburgh in 2000 and 2002 respectively, a Master of Public Health (MPH) in epidemiology in 2004 from University of Pittsburgh Graduate School of Public Health, and a Master of Business Administration (MBA) from Tepper School of Business at Carnegie Mellon University in 2008.[4][10] Omalu served as chief medical examiner of San Joaquin County, California from 2007 until he resigned in 2017 after accusing the county's Sheriff, who doubles as Coroner, of repeatedly interfering with death investigations to protect law enforcement officers who killed people.[5] An assistant forensic pathologist who joined the office for the opportunity to work with Omalu resigned a few days earlier citing similar allegations.[6] Omalu is a professor in the UC Davis Department of Medical Pathology and Laboratory Medicine.[7] Research on CTE{{Main|Concussions in American football|Concussions in sport|Chronic traumatic encephalopathy|l3=Chronic traumatic encephalopathy (CTE)}}Omalu's autopsy of former Pittsburgh Steelers player Mike Webster in 2002 led to the re-emergence of awareness of a neurologic condition associated with chronic head trauma called chronic traumatic encephalopathy, or CTE, which had been previously described in boxers[8] and other professional athletes. Webster had died suddenly and unexpectedly following years of struggling with cognitive and intellectual impairment, destitution, mood disorders, depression, drug abuse, and suicide attempts. Although Webster's brain looked normal at autopsy, Omalu conducted independent and self-financed tissue analyses.[15] He suspected that Webster suffered from dementia pugilistica, which is a form of dementia that is induced by repeated blows to the head, a condition found previously in boxers. Using specialized staining, Omalu found large accumulations of tau protein in Webster's brain, which affect mood, emotions, and executive functions similar to the way that clumps of beta-amyloid protein contribute to Alzheimer's disease.[15] Together with colleagues in the Department of Pathology at the University of Pittsburgh, Omalu published his findings in the journal Neurosurgery in 2005 in a paper titled "Chronic Traumatic Encephalopathy in a National Football League Player." In it, Omalu called for further study of the disease: "We herein report the first documented case of long-term neurodegenerative changes in a retired professional NFL player consistent with chronic traumatic encephalopathy (CTE). This case draws attention to a disease that remains inadequately studied in the cohort of professional football players, with unknown true prevalence rates."[9] Omalu believed the National Football League (NFL) doctors would be "pleased" to read it and that his research could be used to "fix the problem."[15] The paper received little attention initially, but members of the NFL's Mild Traumatic Brain Injury (MTBI) Committee later called for its retraction in May 2006.[10] Their letter requesting the retraction characterized Omalu's description of CTE as "completely wrong" and called the paper "a failure."[3] Omalu later partnered with Julian Bailes, a neurosurgeon, concussion researcher, and then chairman of the Department of Neurosurgery at West Virginia University School of Medicine, and West Virginia attorney Robert P. Fitzsimmons to found the Brain Injury Research Institute which established a brain and tissue bank.[3] In November 2006, Omalu published a second Neurosurgery paper based on his findings in the brain of former NFL player Terry Long, who suffered from depression and committed suicide in 2005. Though Long died at 45, Omalu found tau protein concentrations more consistent with "a 90-year-old brain with advanced Alzheimer's."[15] As with Mike Webster, Omalu asserted that Long's football career had caused later brain damage and depression.[11] Omalu also found evidence of CTE in the brains of retired NFL players Justin Strzelczyk (d. 2004 at 36 years old), Andre Waters (d. 2006 at 44), and Tom McHale (d. 2008 at 45). In summer 2007, Bailes presented his and Omalu's findings to NFL Commissioner Roger Goodell at a league-wide concussion summit. Bailes later said that the research was "dismissed". The NFL's MTBI committee chair, Dr. Ira Casson, told the press: "In my opinion, the only scientifically valid evidence of a chronic encephalopathy in athletes is in boxers and in some Steeplechase jockeys."[10] The NFL did not publicly acknowledge the link between concussions sustained in football and long-term neurological effects until December 2009,[10] seven years after Omalu's discovery. However, as late as 2013, the annual meeting of the American Academy of Clinical Neuropsychology (AACN) included a debate between two sports concussion experts regarding the validity (or existence) of CTE.[12] Finally, in March 2016, the NFL's senior vice president for health and safety policy, Jeff Miller, testified before congress that the NFL now believed that there was a link between football and CTE.[13] Omalu has also discovered CTE in the brains of military veterans, publishing the first documented case in a November 2011 article.[14] Omalu found evidence of CTE in a 27-year-old Iraq War veteran who suffered from post-traumatic stress disorder (PTSD) and later committed suicide. Omalu's paper links PTSD to the CTE spectrum of diseases and calls for further study. Omalu is lead author in a study published in November 2017[15] that for the first time confirmed CTE in a living person. A chemical tracer, FDDNP, binds to tau proteins, detectable by positron emission tomography, and associated with the distinctive topographical distributions characteristic of CTE. Tested on at least a dozen former NFL players, it was confirmed postmortem in former linebacker Fred McNeill.[16] Stephon Clark report{{Main|Shooting of Stephon Clark}}In March 2018 Omalu conducted an independent autopsy of Stephon Clark, who had been shot by Sacramento Police officers. On March 30, he released his findings, stating that Clark had been shot eight times from the back or side, adding, "You could reasonably conclude that he received seven gunshot wounds from his back."[17][18] In popular media{{see also|Concussion (2015 film)}}Omalu's efforts to study and publicize CTE in the face of NFL opposition were reported in a GQ magazine article in 2009 by journalist Jeanne Marie Laskas.[19] The article was later expanded by Laskas into a book, Concussion (Penguin Random House, 2015), and adapted into a film of the same name. In the film, Omalu, portrayed by Will Smith, is the central character. The film has been criticized for not being truthful to the actual events.[20][21] Nevertheless, the movie's production led to the creation of a foundation named after Omalu to advance CTE and concussion research.[22] In September 2016, Omalu attracted media attention when he suggested on Twitter that Hillary Clinton was possibly poisoned and advised members of her presidential campaign to "perform toxicologic analysis of Ms. Clinton's blood." He further tweeted, "I do not trust Mr. Putin and Mr. Trump. With those two, all things are possible."[23] Omalu's book Truth Doesn't Have a Side: My Alarming Discovery about the Danger of Contact Sports was published in August 2017 by HarperCollins.[24][25] He previously wrote Play Hard, Die Young: Football Dementia, Depression, and Death, published in 2008. Personal lifeOmalu is married to Prema Mutiso, originally from Kenya. They live in Elk Grove, CA and have two children, Ashly and Mark.[3] He is a practicing Catholic and became a naturalized U.S. citizen in February 2015.[26] See also
References1. ^1 "About Bennet Omalu", Bennet Omalu Foundation website. 2. ^1 {{cite web | url=https://www.wsj.com/articles/the-doctor-the-nfl-tried-to-silence-1448399061?mod=e2tw | title=The Doctor the NFL Tried to Silence | work=The Wall Street Journal | date=24 November 2015 | accessdate=25 November 2015 | last=Laskas|first= Jeanne Marie| authorlink= Jeanne Marie Laskas | archiveurl = https://web.archive.org/web/20151125020721/http://www.wsj.com/articles/the-doctor-the-nfl-tried-to-silence-1448399061 | archivedate =25 November 2015| deadurl=no}} 3. ^1 2 3 4 5 {{Cite book|title = Concussion|publisher = Random House Trade Paperbacks|date = 2015-11-24|isbn = 9780812987577|first = Jeanne Marie|last = Laskas}} 4. ^[https://www.ucdmc.ucdavis.edu/pathology/our_team/faculty/OmaluB/BennetIOmaluMD,MBA,MPH,CPE,CurriculumVitaeAndTestimonies,August2015.pdf "CV: Bennet Omalu"], UC Davis Medical Center 5. ^{{cite news |last = Small |first = Julie |title = Autopsy Doctor Resigns, Says Sheriff Overrode Death Findings to Protect Officers |newspaper = KQED |date = December 4, 2017 |url = https://ww2.kqed.org/news/2017/12/04/autopsy-doctors-sheriff-overrode-death-findings-to-protect-law-enforcement/ |access-date = 2017-12-11 }} 6. ^{{cite news |last = Small |first = Julie |title = Autopsy Doctor Quits, Alleges Sheriff Interfered in Death Probes |newspaper = KQED |date = November 27, 2017 |url = https://ww2.kqed.org/news/2017/11/27/autopsy-doctor-quits-alleges-sheriff-interfered-in-death-probes/ |access-date = 2017-12-11 }} 7. ^1 {{cite web|title=Bennet Omalu, M.D., M.B.A., MPH, CPE, DABP-AP, CP, FP, NP|url=http://www.ucdmc.ucdavis.edu/pathology/our_team/faculty/OmaluB.html|publisher=University of California, Davis Department of Pathology and Laboratory Medicine|accessdate=1 September 2015}} 8. ^Sabharwal RK, Sanchetee PC, Sethi PK, Dhamija RM. Chronic traumatic encephalopathy in boxers. J Assoc Physicians India. 1987 Aug;35(8):571-3. 9. ^{{Cite journal|title = Chronic traumatic encephalopathy in a National Football League player|journal = Neurosurgery|date = 2005-07-01|issn = 1524-4040|pmid = 15987548|pages = 128-134; discussion 128-134|volume = 57|issue = 1|first = Bennet I.|last = Omalu|first2 = Steven T.|last2 = DeKosky|first3 = Ryan L.|last3 = Minster|first4 = M. Ilyas|last4 = Kamboh|first5 = Ronald L.|last5 = Hamilton|first6 = Cyril H.|last6 = Wecht|doi=10.1227/01.neu.0000163407.92769.ed}} 10. ^1 2 {{cite web|title = Timeline: The NFL's Concussion Crisis – League of Denial: The NFL's Concussion Crisis - FRONTLINE|url = https://www.pbs.org/wgbh/pages/frontline/sports/league-of-denial/timeline-the-nfls-concussion-crisis/#2006|website = FRONTLINE|publisher = PBS |accessdate = 2015-11-09}} 11. ^{{Cite journal|title = Chronic traumatic encephalopathy in a national football league player: part II|journal = Neurosurgery|date = 2006-11-01|issn = 1524-4040|pmid = 17143242|pages = 1086-1092; discussion 1092-1093|volume = 59|issue = 5|doi = 10.1227/01.NEU.0000245601.69451.27|first = Bennet I.|last = Omalu|first2 = Steven T.|last2 = DeKosky|first3 = Ronald L.|last3 = Hamilton|first4 = Ryan L.|last4 = Minster|first5 = M. Ilyas|last5 = Kamboh|first6 = Abdulrezak M.|last6 = Shakir|first7 = Cyril H.|last7 = Wecht}} 12. ^[https://www.sciencedaily.com/releases/2013/06/130619132354.htm "Sports concussions debate: Does CTE really exist?"]. Science Daily. Loyola University Health System. June 19, 2013. 13. ^{{Cite news|url=https://www.nytimes.com/2016/03/16/sports/nfl-concussions-cte-football-jeff-miller.html|title=N.F.L. Shifts on Concussions, and Game May Never Be the Same|last=Belson|first=Ken|date=2016-03-15|work=The New York Times|access-date=2018-01-03|last2=Schwarz|first2=Alan|language=en-US|issn=0362-4331}} 14. ^{{Cite journal|title = Chronic traumatic encephalopathy in an Iraqi war veteran with posttraumatic stress disorder who committed suicide|journal = Neurosurgical Focus|date = 2011-11-01|issn = 1092-0684|pmid = 22044102|pages = E3|volume = 31|issue = 5|doi = 10.3171/2011.9.FOCUS11178|first = Bennet|last = Omalu|first2 = Jennifer L.|last2 = Hammers|first3 = Julian|last3 = Bailes|first4 = Ronald L.|last4 = Hamilton|first5 = M. Ilyas|last5 = Kamboh|first6 = Garrett|last6 = Webster|first7 = Robert P.|last7 = Fitzsimmons}} 15. ^{{cite journal |last = Omalu |first = Bennet |author2 =|display-authors=et al |title = Postmortem Autopsy-Confirmation of Antemortem [F-18]FDDNP-PET Scans in a Football Player With Chronic Traumatic Encephalopathy |journal = Neurosurgery |date = 2017 |doi = 10.1093/neuros/nyx536 }} 16. ^{{cite news |last = Kounang |first = Nadia |title = Ex-NFL player confirmed as 1st case of CTE in living patient. He resigned his coroner position in 2017. |newspaper = CNN |date = November 16, 2017 |url = https://www.cnn.com/2017/11/16/health/cte-confirmed-in-first-living-person-bn/ |access-date = 2017-12-11 }} 17. ^{{Cite news|url=https://www.usatoday.com/story/news/nation/2018/03/30/stephon-clark-independent-autopsy-results-announced-friday/472507002/|title=Stephon Clark shot 8 times, mostly in back, independent autopsy finds|work=USA TODAY|access-date=2018-04-01|language=en}} 18. ^{{Cite news|url=https://www.nytimes.com/2018/03/30/us/stephon-clark-independent-autopsy.html|title=Stephon Clark Was Shot 8 Times Primarily in His Back, Family-Ordered Autopsy Finds|last=Robles|first=Frances|date=2018-03-30|work=The New York Times|access-date=2018-04-01|last2=Real|first2=Jose A. Del|language=en-US|issn=0362-4331}} 19. ^1 2 3 4 {{Cite news|title = Game Brain: Football Players and Concussions|url = https://www.gq.com/story/nfl-players-brain-dementia-study-memory-concussions|work = GQ| last=Laskas|first= Jeanne Marie|accessdate = 9 November 2015| archiveurl = https://web.archive.org/web/20151111053002/http://www.gq.com/story/nfl-players-brain-dementia-study-memory-concussions | archivedate= 11 November 2015| deadurl=no}} 20. ^Engber, Daniel (December 21, 2015). "Concussion Lies: The film about the NFL's apparent CTE epidemic feeds the pervasive national myths about head trauma.". Slate. 21. ^"'Concussion' Subject Bennet Omalu Exaggerated His Role, Researchers Say". CBS New York. December 17, 2015. 22. ^{{cite web|title = About the Foundation {{!}} Bennet Omalu Foundation|url = http://bennetomalufoundation.org/about-the-foundation/|website = bennetomalufoundation.org|accessdate = 2015-12-25}} 23. ^{{cite web|last=Boren |first=Cindy |url=https://www.washingtonpost.com/news/early-lead/wp/2016/09/12/the-man-who-discovered-cte-thinks-hillary-clinton-may-have-been-poisoned/ |title=The man who discovered CTE thinks Hillary Clinton may have been poisoned |publisher=The Washington Post |date= |accessdate=2016-09-13}} 24. ^{{cite news|last1=Peterson|first1=Gary|title=Why it took a foreign-born doctor to blow the whistle on the NFL's concussion epidemic |url=http://www.eastbaytimes.com/2017/08/24/bennet-omalu/|work=Bay Area News Group|date=August 24, 2017}} 25. ^{{cite news|last1=Almond|first1=Elliott|title='Concussion' doc's six sports kids should never play|url= http://www.eastbaytimes.com/2017/08/25/the-concussion-docs-six-sports-kids-should-never-play/|work=Bay Area News Group|date=August 25, 2017}} 26. ^{{cite web|title = Bennet Omalu Foundation launches in Pittsburgh|url = http://www.pghcitypaper.com/Blogh/archives/2015/12/16/bennet-omalu-foundation-launches-in-pittsburgh|website = Pittsburgh City Paper|accessdate = 2016-01-05}} External links
25 : Living people|20th-century Nigerian medical doctors|University of Nigeria, Nsukka alumni|University of Pittsburgh alumni|Tepper School of Business alumni|Federal Government College Enugu alumni|American forensic pathologists|Nigerian pathologists|1968 births|Nigerian emigrants to the United States|University of California, Davis faculty|Concussion activists|American football controversies|Nigerian Roman Catholics|American people of Nigerian descent|American people of Igbo descent|Igbo physicians|People of the Nigerian Civil War|21st-century American physicians|People from Anambra State|20th-century American physicians|American physicians|People with acquired American citizenship|People from Lodi, California|Whistleblowers |
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