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词条 Beta-amyrin 11-oxidase
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Beta-amyrin 11-oxidase
| EC_number = 1.14.13.134
| CAS_number =
| IUBMB_EC_number = 1/14/13/134
| GO_code =
| image =
| width =
| caption =
}}Beta-amyrin 11-oxidase ({{EC number|1.14.13.134}}, CYP88D6) is an enzyme with systematic name beta-amyrin,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction

beta-amyrin + 2 O2 + 2 NADPH + 2 H+ 11-oxo-beta-amyrin + 3 H2O + 2 NADP+ (overall reaction)

(1a) beta-amyrin + O2 + NADPH + H+ 11alpha-hydroxy-beta-amyrin + H2O + NADP+

(1b) 11alpha-hydroxy-beta-amyrin + O2 + NADPH + H+ 11-oxo-beta-amyrin + 2 H2O + NADP+

Beta-amyrin 11-oxidase requires cytochrome P450.

References

1. ^{{cite journal | vauthors = Seki H, Ohyama K, Sawai S, Mizutani M, Ohnishi T, Sudo H, Akashi T, Aoki T, Saito K, Muranaka T | title = Licorice beta-amyrin 11-oxidase, a cytochrome P450 with a key role in the biosynthesis of the triterpene sweetener glycyrrhizin | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 105 | issue = 37 | pages = 14204–9 | date = September 2008 | pmid = 18779566 | pmc = 2532699 | doi = 10.1073/pnas.0803876105 }}

External links

  • {{MeshName|Beta-amyrin+11-oxidase}}
{{Dioxygenases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 1.14.13

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