| 词条 | Bidnaviridae |
| 释义 |
| taxon = Bidnaviridae | subdivision_ranks = Genus | subdivision = Bidensovirus }}Bidnaviridae is a family of single stranded DNA viruses. Members of this family infect invertebrates. These viruses were once considered members of the family Parvoviridae (subfamily Densovirinae) but their genomes differ greatly from those viruses in size and coding strategy. Because of this they have been classified into a family of their own.[1] VirologyThe virions are icosahedral, not enveloped and ~25 nanometers in diameter. There are two structural proteins in the virion. This family is unique among ssDNA viruses in having a bipartite linear genome. The genome consists of two linear ssDNA segments of ~6 and 6.5 kilobases (kb) that are packaged separately. The complementary strands are also packaged giving rise to 4 distinct types of viral particles. The total genome length is ~13 kb while that of parvoviruses is 4–6 kb. EvolutionComprehensive analysis of bidnavirus genes has shown that these viruses have evolved from a parvovirus ancestor from which they inherit a jelly-roll capsid protein and a superfamily 3 helicase.[2] It has been further suggested that the key event that led to the separation of the bidnaviruses from parvoviruses was the acquisition of the PolB gene. A likely scenario has been proposed under which the ancestral parvovirus genome was integrated into a large virus-derived DNA transposon of the Polinton/Maverick (polintovirus) family [3] resulting in the acquisition of the polintovirus PolB gene along with terminal inverted repeats. Bidnavirus genes for a minor structural protein (putative receptor-binding protein) and a potential novel antiviral defense modulator were derived from dsRNA viruses (Reoviridae) and dsDNA viruses (Baculoviridae), respectively.[2] TaxonomyOnly one genus in this family is currently recognised: Bidensovirus. References1. ^Virus Taxonomy: Ninth Report of the International Committee on Taxonomy of Viruses (2011) {{ISBN|978-0123846846}} {{Taxonbar|from=Q4904207}}2. ^1 {{cite journal |vauthors=Krupovic M, Koonin EV|title=Evolution of eukaryotic single-stranded DNA viruses of the Bidnaviridae family from genes of four other groups of widely different viruses|journal=Sci Rep|date=2014|volume=4|page=5347|doi=10.1038/srep05347|pmid=24939392|url=http://www.nature.com/srep/2014/140618/srep05347/full/srep05347.html|pmc=4061559}} 3. ^{{cite journal |vauthors=Krupovic M, Bamford DH, Koonin EV|title=Conservation of major and minor jelly-roll capsid proteins in Polinton (Maverick) transposons suggests that they are bona fide viruses|journal=Biol Direct|date=2014|volume=9|issue=1|page=6|doi=10.1186/1745-6150-9-6|pmid=24773695|url=http://www.biologydirect.com/content/9/1/6|pmc=4028283}} 2 : Single-stranded DNA viruses|Virus families |
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