Bierwirth is a German surname. Notable people with the surname include:

• John Bierwirth ({{circa}} 1924–2013), American lawyer and businessman
• Karl Bierwirth (1907–1955), German weightlifter
• Petra Bierwirth (born 1960), German politician
• Rudolph Bierwirth (1899–1993), Australian army officer

• Ernesto Sanz
• Ernesto Sastre
• Ernesto Screpanti
• Ernesto Seikō Arakaki Arakaki
• Ernesto Sinclair
• Ernesto Tagliaferri
• Ernesto Tamayo
• Ernest Othmer Thompson
• Ernest O. Thompson
• Ernesto Tomasi
• Ernesto Viceconte
• Ernesto Vázquez
• Ernest Owens
• Ernestown, Ontario
• Ernestown Secondary School
• Ernestowo
• Ernesto Zedillo Ponce de LeA3n
• Ernesto Álvarez
• Ernest Parkes
• Ernest Pascoe
• Ernest Pass Memorial Ground
• Ernest Paul
• Ernest Payne (football)
• Ernest Payne (footballer)
• Ernest Peak