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词条 Bisnortilidine
释义

  1. References

{{Chembox
| ImageFile = Bisnortilidine structure.svg
| ImageSize = 200px
| ImageAlt =
| IUPACName = Ethyl (1R,2S)-2-amino-1-phenylcyclohex-3-ene-1-carboxylate
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo =
| PubChem = 162740
| ChemSpiderID = 454879
| InChI=1S/C15H19NO2/c1-2-18-14(17)15(11-7-6-10-13(15)16)12-8-4-3-5-9-12/h3-6,8-10,13H,2,7,11,16H2,1H3/t13-,15+/m0/s1
| InChIKey= BTKAMSWFNMGLGM-DZGCQCFKSA-N
| SMILES =CCOC(=O)[C@]1(CCC=C[C@@H]1N)C2=CC=CC=C2 }}
|Section2={{Chembox Properties
| C=15 | H=19 | N=1 | O=2
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt = }}
}}

Bisnortilidine is an opioid metabolite.[1] It is formed from tilidine by demethylation in the liver.

References

1. ^{{ cite journal | last1 = Wustrow | first1 = I. | last2 = Riedel | first2 = K. D. | last3 = Mikus | first3 = G. | last4 = Weiss | first4 = J. | title = In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | year = 2012 | volume = 385 | issue = 6 | pages = 633–9 | doi = 10.1007/s00210-012-0737-z | pmid = 22349139 }}
{{organic-compound-stub}}

2 : Human metabolites|Cyclohexenes

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