词条 | Bisnortilidine |
释义 |
| ImageFile = Bisnortilidine structure.svg | ImageSize = 200px | ImageAlt = | IUPACName = Ethyl (1R,2S)-2-amino-1-phenylcyclohex-3-ene-1-carboxylate | OtherNames = |Section1={{Chembox Identifiers | CASNo = | PubChem = 162740 | ChemSpiderID = 454879 | InChI=1S/C15H19NO2/c1-2-18-14(17)15(11-7-6-10-13(15)16)12-8-4-3-5-9-12/h3-6,8-10,13H,2,7,11,16H2,1H3/t13-,15+/m0/s1 | InChIKey= BTKAMSWFNMGLGM-DZGCQCFKSA-N | SMILES =CCOC(=O)[C@]1(CCC=C[C@@H]1N)C2=CC=CC=C2 }} |Section2={{Chembox Properties | C=15 | H=19 | N=1 | O=2 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }} Bisnortilidine is an opioid metabolite.[1] It is formed from tilidine by demethylation in the liver. References1. ^{{ cite journal | last1 = Wustrow | first1 = I. | last2 = Riedel | first2 = K. D. | last3 = Mikus | first3 = G. | last4 = Weiss | first4 = J. | title = In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine | journal = Naunyn-Schmiedeberg's Archives of Pharmacology | year = 2012 | volume = 385 | issue = 6 | pages = 633–9 | doi = 10.1007/s00210-012-0737-z | pmid = 22349139 }} {{organic-compound-stub}} 2 : Human metabolites|Cyclohexenes |
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