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词条 Brachyurin
释义

  1. References

  2. External links

{{Infobox enzyme
| Name = Brachyurin
| EC_number = 3.4.21.32
| CAS_number = 848900-32-3
| IUBMB_EC_number = 3/4/21/32
| GO_code =
| image =
| width =
| caption =
}}

Brachyurin ({{EC number|3.4.21.32}}, Uca pugilator collagenolytic proteinase, crab protease I, crab protease II) is an enzyme.[1][2][3][4][5][6] This enzyme catalyses the Hydrolysis of proteins, with broad specificity for peptide bonds. Native collagen is cleaved about 75% of the length of the molecule from the N-terminus.

This enzyme is isolated from hepatopancreas of the fiddler crab, Uca pugilator.

References

1. ^{{cite journal | vauthors = Hurion N, Fromentin H, Keil B | title = Specificity of the collagenolytic enzyme from the fungus Entomophthora coronata: comparison with the bacterial collagenase from Achromobacter iophagus | journal = Archives of Biochemistry and Biophysics | volume = 192 | issue = 2 | pages = 438–45 | date = February 1979 | pmid = 219780 | doi = 10.1016/0003-9861(79)90113-9 }}
2. ^{{cite journal | title = Collagenolytic protease from fiddler crab (Uca pugilator) | vauthors = Grant GA, Eisen AZ, Bradshaw RA |journal = Methods Enzymol. |date = 1981 |volume = 80 |pages = 722–734 |pmid = |doi=10.1016/s0076-6879(81)80055-9}}
3. ^{{cite journal | vauthors = Welgus HG, Grant GA, Jeffrey JJ, Eisen AZ | title = Substrate specificity of the collagenolytic serine protease from Uca pugilator: studies with collagenous substrates | journal = Biochemistry | volume = 21 | issue = 21 | pages = 5183–9 | date = October 1982 | pmid = 6756469 | doi = 10.1021/bi00264a012 }}
4. ^{{cite journal | vauthors = Welgus HG, Grant GA | title = Degradation of collagen substrates by a trypsin-like serine protease from the fiddler crab Uca pugilator | journal = Biochemistry | volume = 22 | issue = 9 | pages = 2228–33 | date = April 1983 | pmid = 6305411 | doi = 10.1021/bi00278a026 }}
5. ^{{cite journal | vauthors = Klimova OA, Borukhov SI, Solovyeva NI, Balaevskaya TO | title = The isolation and properties of collagenolytic proteases from crab hepatopancreas | journal = Biochemical and Biophysical Research Communications | volume = 166 | issue = 3 | pages = 1411–20 | date = February 1990 | pmid = 2154979 | doi = 10.1016/0006-291x(90)91024-m }}
6. ^{{cite journal | vauthors = Lu PJ, Liu HC, Tsai IH | title = The midgut trypsins of shrimp (Penaeus monodon). High efficiency toward native protein substrates including collagens | journal = Biological Chemistry Hoppe-Seyler | volume = 371 | issue = 9 | pages = 851–9 | date = September 1990 | pmid = 1963309 | doi = 10.1515/bchm3.1990.371.2.851 }}

External links

  • {{MeshName|Brachyurin}}
{{Serine endopeptidases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}

1 : EC 3.4.21

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