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Brigham is a surname. Notable people with the surname include: - Asa Brigham (1788–1844), Texas politician and businessman
- Albert Perry Brigham (1855–1932), American geologist and clergyman.
- Amariah Brigham (1798–1849), American psychiatrist
- Carl Brigham (1890–1943), American psychologist at Princeton University, developer of the progenitor of the SAT test
- Charles Brigham (1841–1925), American architect
- Harold Brigham (1914–1978), English footballer who played for Nottingham Forest. Stoke City and York City
- Louise Brigham (1875-1956), American designer and teacher
- Paul Brigham (1746–1824), Revolutionary soldier and American politician
- Peter Bent Brigham (1807–1877), American businessman and philanthropist
- Philip Brigham, Canadian rock singer, composer and guitarist
- William Tufts Brigham (1841–1926), American botanist and ethnologist, first director of the Bernice P. Bishop Museum (1898–1918)
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