词条 | Brigitta Stockinger |
释义 |
| name = Gitta Stockinger | birth_name = Brigitta Stockinger | native_name_lang = | image = | image_size = | alt = | caption = | birth_date = | birth_place = | other_names = | residence = | citizenship = | nationality = | fields = {{Plainlist|
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| patrons = | alma_mater = University of Mainz (PhD) | thesis_title = | thesis_url = | thesis_year = | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = | author_abbrev_bot = | author_abbrev_zoo = | influences = | influenced = | awards = {{Plainlist|
| signature = | signature_alt = | website = {{URL|nimr.mrc.ac.uk/research/gitta-stockinger}} | footnotes = | spouse = | children = }}Brigitta Stockinger, FMedSci, FRS, is a molecular immunologist in the Francis Crick Institute London. Stockinger's research has contributed insights into the regulation and maintenance of peripheral T cell immune responses.[1][2][3][4][5][6][7][8][9][10] EducationStockinger was educated at the University of Mainz where she was awarded a PhD in Biology. Career
Awards and honoursStockinger was elected a Fellow of the Royal Society in 2013, her nomination reads: {{centred pull quote|Brigitta Stockinger has contributed insights regulation and maintenance of peripheral T cell immune responses. She was the first to define mechanisms underlying the differentiation of Th17 cells and demonstrated substantial pasticity in TH17 cell function depending on the inflammatory environment. Stockinger identified the Aryl hydrocarbon receptor (AhR) as connector between the immune system and environmental stimuli, showing that it shapes the functional differentiation of Th17 effector cells. The AhR links their role in host defence as well as their role in autoimmunity to environmental factors. Research into the physiological roles of AhR in the immune system beyond its role in toxicology provides a major breakthrough for both disciplines.[11]}} In 2008, she was elected a member of European Molecular Biology Organization (EMBO). References1. ^{{Cite journal | doi = 10.1038/nature06881| title = The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins| journal = Nature| volume = 453| issue = 7191| pages = 106–109| year = 2008| last1 = Veldhoen | first1 = M. | last2 = Hirota | first2 = K. | last3 = Westendorf | first3 = A. M. | last4 = Buer | first4 = J. | last5 = Dumoutier | first5 = L. | last6 = Renauld | first6 = J. C. | last7 = Stockinger | first7 = B. | pmid=18362914}} {{FRS 2013}}{{Authority control}}{{DEFAULTSORT:Stockinger, Brigitta}}{{UK-scientist-stub}}2. ^{{Cite journal | doi = 10.1038/ni.1659| pmid = 18931678| title = Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9–producing subset| journal = Nature Immunology| volume = 9| issue = 12| pages = 1341–1346| year = 2008| last1 = Veldhoen | first1 = M. | last2 = Uyttenhove | first2 = C. | last3 = Van Snick | first3 = J. | last4 = Helmby | first4 = H. | last5 = Westendorf | first5 = A. | last6 = Buer | first6 = J. | last7 = Martin | first7 = B. | last8 = Wilhelm | first8 = C. | last9 = Stockinger | first9 = B. }} 3. ^{{Cite journal | pmid = 16473830| year = 2006| author1 = Veldhoen| first1 = M| title = TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells| journal = Immunity| volume = 24| issue = 2| pages = 179–89| last2 = Hocking| first2 = R. J.| last3 = Atkins| first3 = C. J.| last4 = Locksley| first4 = R. M.| last5 = Stockinger| first5 = B| doi = 10.1016/j.immuni.2006.01.001}} 4. ^{{Cite journal | doi = 10.1186/1741-7007-11-115| pmid = 24279517| pmc = 3842812| title = Open questions: A few that need answers in immunology| journal = BMC Biology| volume = 11| pages = 115| year = 2013| last1 = Stockinger | first1 = B. }} 5. ^{{AcademicSearch|23308670}} 6. ^{{Scopus|id=7005193606}} 7. ^{{Cite journal | pmid = 15128781| year = 2004| author1 = Vieira| first1 = P. L.| title = IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells| journal = Journal of Immunology| volume = 172| issue = 10| pages = 5986–93| last2 = Christensen| first2 = J. R.| last3 = Minaee| first3 = S| last4 = O'Neill| first4 = E. J.| last5 = Barrat| first5 = F. J.| last6 = Boonstra| first6 = A| last7 = Barthlott| first7 = T| last8 = Stockinger| first8 = B| last9 = Wraith| first9 = D. C.| last10 = O'Garra| first10 = A | doi=10.4049/jimmunol.172.10.5986}} 8. ^{{Cite journal | doi = 10.1016/j.coi.2007.04.005| title = Differentiation and function of Th17 T cells| journal = Current Opinion in Immunology| volume = 19| issue = 3| pages = 281–6| year = 2007| last1 = Stockinger | first1 = B. | last2 = Veldhoen | first2 = M. | pmid=17433650}} 9. ^{{Cite journal | doi = 10.1038/nri3362| pmid = 23197111| title = The resolution of inflammation| journal = Nature Reviews Immunology| volume = 13| issue = 1| pages = 59–66| year = 2012| last1 = Buckley | first1 = C. D. | last2 = Gilroy | first2 = D. W. | last3 = Serhan | first3 = C. N. | last4 = Stockinger | first4 = B. | last5 = Tak | first5 = P. P. }} 10. ^{{Cite journal | pmid = 8642293| year = 1996| author1 = Stockinger| first1 = B| title = B cells solicit their own help from T cells| journal = The Journal of Experimental Medicine| volume = 183| issue = 3| pages = 891–9| last2 = Zal| first2 = T| last3 = Zal| first3 = A| last4 = Gray| first4 = D| pmc = 2192359 | doi=10.1084/jem.183.3.891}} 11. ^{{Cite web | url=http://royalsociety.org/people/brigitta-stockinger/ | title=| Royal Society}} 6 : Female Fellows of the Royal Society|Fellows of the Royal Society|Members of the European Molecular Biology Organization|Living people|Date of birth missing (living people)|Year of birth missing (living people) |
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