| 词条 | C5orf45 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| 释义 |
Model organisms
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion.[4][11] Twenty five tests were carried out on mutant mice and one significant abnormality was observed: male homozygote mutants were infertile.[4] References1. ^1 {{cite web | title = Chromosome 5 open reading frame 45| url = https://www.ncbi.nlm.nih.gov/gene/51149| accessdate = 2011-12-07}} 2. ^{{cite web |url=http://www.sanger.ac.uk/mouseportal/phenotyping/MBKT/salmonella-challenge/ |title=Salmonella infection data for 3010026O09Rik |publisher=Wellcome Trust Sanger Institute}} 3. ^{{cite web |url=http://www.sanger.ac.uk/mouseportal/phenotyping/MBKT/citrobacter-challenge/ |title=Citrobacter infection data for 3010026O09Rik |publisher=Wellcome Trust Sanger Institute}} 4. ^1 2 {{cite journal | doi = 10.1111/j.1755-3768.2010.4142.x | title = The Sanger Mouse Genetics Programme: High throughput characterisation of knockout mice | year = 2010 | author = Gerdin AK | journal = Acta Ophthalmologica | volume = 88 | pages = 925–7 }} 5. ^Mouse Resources Portal, Wellcome Trust Sanger Institute. 6. ^{{cite web |url=http://www.knockoutmouse.org/martsearch/search?query=3010026O09Rik |title=International Knockout Mouse Consortium}} 7. ^{{cite web |url=http://www.informatics.jax.org/searchtool/Search.do?query=MGI:4431715 |title=Mouse Genome Informatics}} 8. ^{{Cite journal| last1 = Skarnes |first1 =W. C.| doi = 10.1038/nature10163 | last2 = Rosen | first2 = B.| last3 = West | first3 = A. P.| last4 = Koutsourakis | first4 = M.| last5 = Bushell | first5 = W.| last6 = Iyer | first6 = V.| last7 = Mujica | first7 = A. O.| last8 = Thomas | first8 = M.| last9 = Harrow | first9 = J.| last10 = Cox | first10 = T.| last11 = Jackson | first11 = D.| last12 = Severin | first12 = J.| last13 = Biggs | first13 = P.| last14 = Fu | first14 = J.| last15 = Nefedov | first15 = M.| last16 = De Jong | first16 = P. J.| last17 = Stewart | first17 = A. F.| last18 = Bradley | first18 = A. | title = A conditional knockout resource for the genome-wide study of mouse gene function | journal = Nature | volume = 474 | issue = 7351 | pages = 337–342 | year = 2011 | pmid = 21677750 | pmc =3572410 }} 9. ^{{cite journal | doi = 10.1038/474262a | title = Mouse library set to be knockout | year = 2011 | author = Dolgin E | journal = Nature | volume = 474 | issue = 7351 | pages = 262–3 | pmid = 21677718 }} 10. ^{{cite journal | doi = 10.1016/j.cell.2006.12.018 | title = A Mouse for All Reasons | year = 2007 | journal = Cell | volume = 128 | pages = 9–13 | pmid = 17218247 |vauthors=Collins FS, Rossant J, Wurst W | issue = 1 }} 11. ^{{cite journal|vauthors=van der Weyden L, White JK, Adams DJ, Logan DW | title=The mouse genetics toolkit: revealing function and mechanism. | journal=Genome Biol | year= 2011 | volume= 12 | issue= 6 | pages= 224 | pmid=21722353 | doi=10.1186/gb-2011-12-6-224 | pmc=3218837}} Further reading
| last1 = Wiemann | first1 = S. | last2 = Arlt | first2 = D. | last3 = Huber | first3 = W. | last4 = Wellenreuther | first4 = R. | last5 = Schleeger | first5 = S. | last6 = Mehrle | first6 = A. | last7 = Bechtel | first7 = S. | last8 = Sauermann | first8 = M. | last9 = Korf | first9 = U. | last10 = Pepperkok | first10 = R. | last11 = Sültmann | first11 = H. | last12 = Poustka | first12 = A. | title = From ORFeome to Biology: A Functional Genomics Pipeline | doi = 10.1101/gr.2576704 | journal = Genome Research | volume = 14 | issue = 10b | pages = 2136–2144 | year = 2004 | pmid = 15489336 | pmc =528930 }}
| last1 = Lamesch | first1 = P. | last2 = Li | first2 = N. | last3 = Milstein | first3 = S. | last4 = Fan | first4 = C. | last5 = Hao | first5 = T. | last6 = Szabo | first6 = G. | last7 = Hu | first7 = Z. | last8 = Venkatesan | first8 = K. | last9 = Bethel | first9 = G. | doi = 10.1016/j.ygeno.2006.11.012 | last10 = Martin | first10 = P. | last11 = Rogers | first11 = J. | last12 = Lawlor | first12 = S. | last13 = McLaren | first13 = S. | last14 = Dricot | first14 = A. L. | last15 = Borick | first15 = H. | last16 = Cusick | first16 = M. E. | last17 = Vandenhaute | first17 = J. | last18 = Dunham | first18 = I. | last19 = Hill | first19 = D. E. | last20 = Vidal | first20 = M. | title = HORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes | journal = Genomics | volume = 89 | issue = 3 | pages = 307–315 | year = 2007 | pmid = 17207965 | pmc = }}{{refend}}{{gene-5-stub}} 2 : Human proteins|Genes mutated in mice |
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