| 词条 | Carnosol |
| 释义 |
| Watchedfields = | verifiedrevid = | Name = Carnosol | ImageFile = Carnosol.svg | ImageName = Chemical structure of carnosol | IUPACName = | OtherNames = |Section1={{Chembox Identifiers | CASNo = 5957-80-2 | CASNo_Ref = | CASNoOther = | PubChem = 442009 | ChemSpiderID = 390568 | SMILES = CC(C)C1=CC2=C(C(=C1O)O)[C@@]34CCCC([C@@H]3C[C@@H]2OC4=O)(C)C | InChI = 1/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1 | InChIKey = XUSYGBPHQBWGAD-PJSUUKDQBN | StdInChI = 1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1 | StdInChIKey = XUSYGBPHQBWGAD-PJSUUKDQSA-N | MeSHName = }} |Section2={{Chembox Properties | C=20 | H=26 | O=4 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} }}Carnosol is a phenolic diterpene found in the herbs rosemary (Rosmarinus officinalis)[1] and Mountain desert sage (Salvia pachyphylla).[2] It has been studied in-vitro for anti-cancer effects in various cancer cell types.[3] See also
References1. ^{{cite journal | title = Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-κB in mouse macrophages |author1=Ai-Hsiang Lo |author2=Yu-Chih Liang |author3=Shoei-Yn Lin-Shiau |author4=Chi-Tang Ho |author5=Jen-Kun Lin | journal = Carcinogenesis | date = 2002 | volume = 23 | issue = 6 | pages = 983–991 | doi = 10.1093/carcin/23.6.983| pmid = 12082020 }} {{Natural phenol-stub}}2. ^{{cite journal |author1=Ivan C. Guerrero |author2=Lucia S. Andres |author3=Leticia G. Leon |author4=Ruben P. Machin |author5=Jose M. Padron |author6=Javier G. Luis |author7=Jose Delgadillo | title = Abietane Diterpenoids from Salvia pachyphylla and S. clevelandii with Cytotoxic Activity against Human Cancer Cell Lines | journal = J. Nat. Prod. | date = 2006 | volume = 69 | issue = 12 | pages = 1803–1805 | pmid = 17190465 | doi = 10.1021/np060279i }} 3. ^{{cite journal| pmc=3070765 | pmid=21382660 | doi=10.1016/j.canlet.2011.02.005 | volume=305 | issue=1 | title=Carnosol: a promising anti-cancer and anti-inflammatory agent | date=June 2011 | journal=Cancer Lett. | pages=1–7 | author=Johnson JJ}} 3 : Diterpenes|Catechols|Lactones |
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