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词条 Cedrol
释义

  1. See also

  2. References

{{Chembox
| ImageFile = Cedrol skeletal.svg
| ImageSize =
| ImageAlt =
| IUPACName = (1S,2R,5S,7R,8R)-2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undecan-8-ol
| OtherNames =
|Section1={{Chembox Identifiers
| CASNo = 77-53-2
| PubChem = 65575
| ChemSpiderID = 59018
| ChEMBL = 1974890
| SMILES = O[C@@]2(CC[C@]31[C@@H](CC[C@H]1C)C([C@H]2C3)(C)C)C
| StdInChI =1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1
| StdInChIKey = SVURIXNDRWRAFU-OGMFBOKVSA-N
}}
|Section2={{Chembox Properties
| C=15 | H=26 | O=1
| Appearance =
| Density = 1.01 g/mL
| MeltingPtC = 86 to 87
| MeltingPt_ref = [1]
| BoilingPtC = 273
| BoilingPt_ref = [2]
| Solubility = }}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}Cedrol is a sesquiterpene alcohol found in the essential oil of conifers (cedar oil), especially in the genera Cupressus (cypress) and Juniperus (juniper). It has also been identified in Origanum onites, a plant related to oregano.[3] Its main uses are in the chemistry of aroma compounds.[4] It makes up about 19% of cedarwood oil Texas and 15.8% of cedarwood oil Virginia.[5]

Cedrol has not been proven to be toxic in humans. It has been shown to have antioxidant and antiinflamatory along with other beneficial effects. In skin sensitization tests 2/20 people showed negative effects, and on the second test there was no sensitivity found. This compound and ones similar have been found to have antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities. These compounds are used globally in traditional medicine and cosmetics.[6] Results of a 2015 study suggest that cedrol strongly attracts pregnant female mosquitoes after they have fed, which can be used to create cedrol-baited traps.[7]

See also

  • Cedrene, another component of cedar oil

References

1. ^{{Merck12th|id=1961}}
2. ^{{Aldrich|id=22135|name=(+)-Cedrol|accessdate=25 May 2011}}
3. ^{{cite book|editors=Connolly, JD; Hill, RA|title=Dictionary of Terpenoids. Voume 1 Mono- and sesquiterpenoids|year=1991|publisher=Chapman&Hall|isbn=0-412-25770-X|at=SQ02555}}
4. ^{{cite book|author=Breitmeier, E|title=Terpenes: flavors, fragrances, pharmaca, pheromones|year=2006|publisher=Wiley-VCH|isbn=3-527-31786-4|pages=46–47}}
5. ^{{cite web|url=http://swiftcraftymonkey.blogspot.com/2012/02/essential-oils-cedarwood-science-of.html|title=Point of Interest!|author=Susan Barclay-Nichols|work=swiftcraftymonkey.blogspot.com}}
6. ^{{cite web | url = https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+8265 | title = Cedrol | work = TOXNET: Toxicology Data Network}}
7. ^{{cite journal | url=http://www.sciguru.org/newsitem/18734/cedrol-naturally-occurring-bait-malaria-spreading-pregnant-mosquitoes | title=Discovery of an oviposition attractant for gravid malaria vectors of the Anopheles gambiae species complex |author1=Lindh, Jenny |author2=Okal, Michael | journal=Malaria Journal |date=March 2015 | volume=14 | issue=119 | doi=10.1186/s12936-015-0636-0}}

1 : Sesquiterpenes

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