Charles Yorke (1722–1770) was Lord Chancellor of Great Britain.

Charles Yorke may also refer to:

• Charles Yorke, 4th Earl of Hardwicke (1799–1873), British naval commander and Conservative politician
• Charles Yorke, 5th Earl of Hardwicke (1836–1897), British aristocrat, Conservative politician, dandy and bankrupt
• Charles Yorke (British Army officer) (1790–1880)
• Charles Philip Yorke (1764–1834), British politician

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