Cheatle is a surname. Notable people with the surname include:

• Alex Cheatle (born 1994), English singer-songwriter
• Arthur Henry Cheatle (1866–1929), English surgeon
• Duncan Cheatle, British businessman
• George Lenthal Cheatle (1865–1951), English surgeon
• Giles Cheatle (born 1953), English cricketer
• Lauren Cheatle (born 1998), Australian cricketer and daughter of Giles Cheatle
• Syd Cheatle (born 1943), Irish writer

• Mark Lynch (association footballer)
• Mark MacGuigan
• Mark Madsen
• Mark Magnus (wrestler)
• Mark Maguire
• Mark Magwire
• Mark Malaska
• Mark Mallman
• Mark Malloch Brown, Baron Malloch-Brown
• Mark Mallory
• Mark Mancina
• Mark Marabini
• Mark Martin
• Mark Martin (cartoonist)
• Mark Martin (comics)
• Mark Martin (judge)
• Mark Mathabane
• Mark Matkevich
• Mark McCabe
• Mark McClellan
• Mark McCormack
• Mark McCumber
• Mark McGhee
• Mark mcgowan
• Mark McGowan (performance artist)