词条 | Chloroprednisone acetate |
释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = [2-[(6S,8S,9S,10R,13S,14S,17R)-6-Chloro-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate | image = Chloroprednisone acetate.svg | width = | tradename = Localyn, Adremycine, Topilan | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 14066-79-6 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 235970 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = | UNII = Z243A6BHCS | KEGG = | ChEBI = | ChEMBL = | synonyms = Chloroprednisone 21-acetate | C=23|H=27|Cl=1|O=6 | SMILES = CC(=O)OCC(=O)[C@]1(CC[C@@H]2[C@@]1(CC(=O)[C@H]3[C@H]2C[C@@H](C4=CC(=O)C=C[C@]34C)Cl)C)O | StdInChI_Ref = | StdInChI = 1S/C23H27ClO6/c1-12(25)30-11-19(28)23(29)7-5-15-14-9-17(24)16-8-13(26)4-6-21(16,2)20(14)18(27)10-22(15,23)3/h4,6,8,14-15,17,20,29H,5,7,9-11H2,1-3H3/t14-,15-,17-,20+,21-,22-,23-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = RACDDTQBAFEERP-PLTZVPCUSA-N }}Chloroprednisone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. It is the 21-acetate ester of chloroprednisone.[1] References1. ^{{Cite book | title = The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies | author = J. Elks | publisher = Springer | date = 2014 | page = 252}} {{Glucocorticoid receptor modulators}}{{steroid-stub}} 2 : Corticosteroid esters|Glucocorticoids |
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