| 词条 | Cilostamide |
| 释义 |
| ImageFile = Cilostamide.svg | ImageSize = 200px | ImageAlt = | IUPACName = N-Cyclohexyl-N-methyl-4-[(2-oxo-1H-quinolin-6-yl)oxy]butanamide | OtherNames = |Section1={{Chembox Identifiers | IUPHAR_ligand = 5167 | CASNo = 68550-75-4 | PubChem = 2753 | ChEMBL = 34431 | ChemSpiderID = 2651 | InChI=1S/C20H26N2O3/c1-22(16-6-3-2-4-7-16)20(24)8-5-13-25-17-10-11-18-15(14-17)9-12-19(23)21-18/h9-12,14,16H,2-8,13H2,1H3,(H,21,23) | InChIKey= UIAYVIIHMORPSJ-UHFFFAOYSA-N | SMILES = CN(C1CCCCC1)C(=O)CCCOC2=CC3=C(C=C2)NC(=O)C=C3}} |Section2={{Chembox Properties | C=20 | H=26 | N=2 | O=3 | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = }} |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} }}Cilostamide is a PDE3 inhibitor.[1] References1. ^{{cite journal|pmid=24259420|year=2013|last1=De Jonge|first1=HR|last2=Tilly|first2=BC|last3=Hogema|first3=BM|last4=Pfau|first4=DJ|last5=Kelley|first5=CA|last6=Kelley|first6=MH|last7=Melita|first7=AM|last8=Morris|first8=MT|last9=Viola|first9=RM|last10=Forrest|first10=JN|title=CGMP Inhibition of Type 3 Phosphodiesterase is the Major Mechanism by which C-type Natriuretic Peptide Activates CFTR in the Shark Rectal Gland|doi=10.1152/ajpcell.00326.2013|journal=American Journal of Physiology. Cell Physiology|volume=306|pages=C343–C353|pmc=3919979}} {{Phosphodiesterase inhibitors}}{{organic-compound-stub}} 4 : Phosphodiesterase inhibitors|2-Quinolones|Phenol ethers|Butyramides |
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