Pleione may refer to:

• Pleione (mythology), a figure in Greek mythology
• Pleione (star), a star belonging to the Pleiades star cluster
• Pleione (plant), a genus mainly of ground orchids. Prefer to grow on tree-trunks and in rock crevices

• Saint Neots
• Saint Nereus
• Saint Neri
• Saint Nicarete
• Saint Nicasius
• Saint Nicasius of Rheims
• Saint Nicephorus
• Saint Nicetius
• Saint Nicholas, Bishop of Myra
• Saint Nicholas Cathedral
• Saint Nicholas Cathedral (Washington D.C.)
• Saint Nicholas Cathedral (Washington, D.C.)
• Saint Nicholas' Church, Ghent
• Saint-Nicholas-du-Port
• Saint Nicholas High School
• Saint Nicholas in Ukraine
• Saint Nicholas of Japan
• Saint Nicholas of Tolentino
• Saint Nicholas Owen
• Saint Nicholas Peak (Canada)
• Saint Nicholas Pieck
• Saint Nicholas School
• Saint Nicholas School, Essex
• Saint Nicholas Thaumaturgus
• Saint Nicholas the Miracle Worker