Class 159 may refer to:

• British Rail Class 159
• Caledonian Railway 0-4-4T#William Pickersgill

• Elza Temary
• El Zawga El Thania
• Elza İbrahimova
• Elzbieta Bocian
• Elzbieta Ettinger
• Elzbieta Gabryszak
• Elzbieta Gellner
• Elzbieta Jankowska (rower)
• Elzbieta Katolik
• Elzbieta Krawczuk
• Elzbieta Kropa
• Elzbieta Krysinska
• Elzbieta Kuncewicz
• Elzbieta Rabsztyn
• Elzbieta Skowronska-Katolik
• Elzbieta Stachurska
• Elzbieta Trylinska
• Elzear Auguste Cousin de Dommartin
• Elze-Bodenburg railway
• Elze (disambiguation)
• Elz (Eifel)
• Elze-Lohne railway
• Elze-Löhne railway
• Elzey Hughes House
• Elze–Bodenburg railway