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词条 Clocental
释义

  1. See also

  2. References

{{Distinguish|Placental}}{{sedative-stub}}{{Drugbox
| Verifiedfields =
| Watchedfields =
| verifiedrevid =
| IUPAC_name = (1-Ethynylcyclohexyl) N-carbamoylcarbamate
| synonyms = Dolcental
| image = Dolcental.png
| alt = Structural formula
| image2 = Clocental molecule ball.png
| alt2 = Ball-and-stick model of the clocental molecule
| width = 200
| tradename =
| pregnancy_category =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 562-94-7
| ATC_prefix =
| ATC_suffix =
| PubChem =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 10757
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL =
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG =
| C=10 | H=14 | N=2 | O=3
| molecular_weight = 210.22976 g/mol
| smiles = C#CC1(CCCCC1)OC(=O)NC(=O)N
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C10H14N2O3/c1-2-10(6-4-3-5-7-10)15-9(14)12-8(11)13/h1H,3-7H2,(H3,11,12,13,14)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = CQVLNDZXTPGTFD-UHFFFAOYSA-N
}}Clocental (dolcental) is a carbamate-derived sedative hypnotic. It can be prepared by the ethynylation of cyclohexanone followed by reaction with allophanyl chloride.[1]

See also

  • Methylpentynol

References

1. ^Grimme, Walter; Emde, Hans {{Cite patent|DE|959458}} (1957 to Rheinpreussen)
{{Hypnotics and sedatives}}{{GABAAR PAMs}}

5 : Alkynes|Carbamates|Hypnotics|Sedatives|GABAA receptor positive allosteric modulators

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